The excitation of the giant dipole resonance induced by fusion reaction is studied with N/Z asymmetry in the entrance channel. The Time Dependant Hartree Fock solution exhibits a strong dipole vibration which can be associated to a giant vibration along the main axis of the deformed compound nucleus. This dipole motion appears to be non linearly coupled to the shape oscillation leading to a strong modulation of its frequency. These phenomenons can be detected in the gamma-ray emission from hot compound nuclei.Ordered collective motions are a general property of mesoscopic systems. In metallic clusters, electron vibrations are plasmon excitations. In atomic nuclei, oscillations of protons against neutrons generate giant dipole resonances [1,2]. The general way to excite such modes is to use rapidly varying electromagnetic fields associated with photons or generated by fast electrically charged particles. The collective vibrations can also be thermally excited as it was clearly demonstrated in the studies of the γ -emission from hot nuclei [3][4][5][6]. It has been recently proposed that fusion reactions with N/Z asymmetric nuclei may lead to the excitation of a dipole mode because of the presence of a net dipole moment in the entrance channel [7][8][9]. The first experimental indications on the possible existence of such new phenomenon have been reported in [10] for fusion reactions and in [11] for deep inelastic collisions. However, the real nature of such a vibration is still unclear both from the experimental and the theoretical point of view. In particular only semiclassical approaches or schematic models have been used to infer the properties of the generated dipole mode.In this letter, we present the first quantum calculation of pre-equilibrium giant collective vibrations using the time dependent Hartree Fock (TDHF) approach [12][13][14][15]17]. TDHF corresponds to an independent propagation of each single particle wave function in the mean field generated by the ensemble of particles. It does not incorporate the dissipation due to two-body interaction [19][20][21], but takes into account one body mechanisms such as Landau spreading and evaporation damping [22]. The quantal nature of the single particle dynamics is explicitely preserved, which is crucial at low energy both because of shell effects and of the wave dynamics. Moreover TDHF is a strongly non linear theory. Hence it can exhibit new couplings between collective modes.In the time dependent Hartree-Fock (TDHF) approach, the evolution of the single particle density matrix ρ(t) = N n=1 |ϕ n ϕ n | is determined by a Liouville equation,where h(ρ) is the mean-field Hamiltonian. We have used the code built by P. Bonche and coworkers with an effective Skyrme mean-field and SLy 4 parameters [23]. The effect of the isospin asymmmetry in the entrance channel has been first studied in the 20 O + 20 M g fusion reactions at energies close to the Coulomb barrier. Strong quantum effects are expected in these mirror-nuclei reactions leading to the N=Z 40 Ca compou...