Sattabacins and Sattazolins: New Biologically Active Compounds with Antiviral Properties Extracted from a Bacillus sp.

Steroids and alkaloids from the South China Sea spongeAxinellasp.

“…Compound 2 has the molecular formula of C 15 H 21 NO 2 as deduced from Comparison of the 1 H and 13 C NMR spectral data of 1 with those of monomethyl indoles, such as N-methyltryptamine (4) [7] and 2-hydroxy-1-(1H-indol-3-yl)-5-methyl-3-hexanone (7) [9], established the location of the mono-substituted chain on C-3, and the only difference between 2 and 7 was that the carbonyl group in compound 7 was replaced by a hydroxyl group in compound 2. This was proved by the HMBC correlations of H-2 with C-4, C-9, C-1 0 , H-2 0 with C-3, C-4 0 , C-3 0 , and H-3 0 with C-5 0 , C-1 0 .…”

Colistin A and colistin B among inhibitory substances of Paenibacillus polymyxa JB05-01-1

“…P. kobensis M isolated from soil produced mattacin (polymixin M) (Nathaniel et al 2003), and Bacillus sp. strain B-60 produced various inhibitory molecules named sattabacin, hydroxysattabacin, sattazolin, and methylsattazolin, with antiviral activity against herpes simplex viruses types 1 and 2 (HSV1 and HSV2) (Lampis et al 1995). Strains of P. polymyxa have been isolated from diVerent ecological niches including food matrices such as butternut squash, potatoes, rice, and wheat Xour (Fangio et al 2010).…”

Concise access toward chiral hydroxy phenylpropanoids: formal synthesis of virolongin B; kigelin; kurasoin A; 4-hydroxysattabacin, and actinopolymorphol A

“…exhibits potent antiviral properties most notably against herpes simplex viruses type HSV 1and HSV 2. 5 Estrogen receptor dimerizing, actinopolymorphol A (5) was isolated from Actinopolymorpha rutilus (YIM 45725). 6 Neocarazostatin B (6) was originally discovered from the culture of Streptomyces sp.…”