Abstract:BackgroundOchronosis, the musculoskeletal manifestation of alcaptonuria (AKU), is characterized by alterations of the spine and large joints of the limbs similar to those of osteoarthritis. However, some cases of spinal involvement that resembles spondiloarthritis (SpA) have been describe, suggesting a prevalent inflammatory involvement of the joints.ObjectivesTo evaluate the prevalence of inflammatory abnormalities in peripheral joints and enthesis of a cohort of patients affected by AKU.Methodsconsecutive pa… Show more
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