Abstract:BackgroundRecently, the concept of interstitial pneumonia with autoimmune features (IPAF) was proposed by the American Thoracic Society.1 The serologic domain of IPAF is composed of antibodies to extractable nuclear antigens, cyclic citrullinated peptide antibody, a high titer of rheumatoid factor, and a high titer of antinuclear antibody. However, the clinical significance of the serologic domain of IPAF has not yet been evaluated in idiopathic pulmonary fibrosis (IPF).ObjectivesTo investigate the clinical si… Show more
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