Abstract:BackgroundBiologic agents have led to a sea change in the management of inflammatory arthritis however higher risk of opportunistic infections particularly tuberculosis (TB) is well recognised. This has led to the development of TB screening guidelines.ObjectivesThe aim of this study was to investigate the prevalence of latent TB in patients prescribed biologic therapy in a TB endemic area (prevalence 50/100,000) and to assess the risk of subsequent reactivation.MethodsRetrospective case note review of all pat… Show more
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