SAT0210 Brain magnetic resonance imaging (mri) and proton magnetic resonance spectroscopy (1h-mrs) in systemic lupus erythematosus (sle)

Abstract

53 patients were included in control group (Group 2). The Lequesne Index was used to determine the severity of the disease. Results All patients in group 1 and 31 patients in group 2 had knee pain and the mean duration of pain was 51.6+77.5 months in group 1 and 23.4+46.5 months in group 2. The mean Body Mass Index (BMI) was 31.7+5.0 in group 1 and 36.7+4.0 in group 2. According to the results of scintigraphic evaluation, healthy controls were separated into two groups. In group 2A patients who had an increase in uptake at least one joint and in group 2B patients who had no uptake. The mean MSS was 4.2 +1.4 in group 1 and 3.3+1.6 in group 2A. Also the mean MRS of the patients in group 1 were 2.9+0.9 and 0.6+0.5, 0.2+0.4 in group 2A and 2B respectively. The mean score of the Lequesne Index was 8,9+3,6 in group 1 patients. There was a positive correlation between age and MSS (p < 0,05) and BMI and MRS (p < 0,05). Also there was a strong correlation between Lequesne OA Severity Index Score the age of the patients in group 1 but no correlation with the MSS. According to the clinical and/or radiological criteria sensitivity of bone scintigraphy was 98.2%, specifity was 57.1%, positive predictive value was 76% and negative predictive value was 96%. Conclusion Our results suggest that 99 m technetium scintigraphy is a better quantifying method in assessing the changes of OA especially in early cases.