SAT0064 High MMP3 serum levels are associated with extensive structural damage in patients with early, treatment naive rheumatoid arthritis (RA): two years prospective clinical and ultrasonographic study
Abstract:ObjectivesTo investigate the association of high baseline MMP-3 serum levels with hands and feet joints structural damage progression, estimated by ultrasonography (US), in patients with early, treatment “naïve” RA without X-ray visible erosions.MethodsSixty-three pts. (9 males and 54 females; mean age 53.4 yrs 21–81±14.1) with early RA (EULAR/ACR 2010 criteria) and symptom duration of ≤12 months (mean duration of 3.8 months) had baseline serum MMP-3 levels tested. Patients had been DMARDs/glucocorticoid naïve… Show more
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