SAT-430 A Phase 1 Study in Healthy Volunteers to Assess the Safety, Tolerability, and Pharmacokinetics of ONO-5788: A Novel Oral Small Molecule Somatostatin Receptor Type-2 Agonist
Abstract:ONO-5788 is a novel low molecular weight orally administered molecule with potent and selective agonistic effects at the human SST2 receptor subtype. ONO-5788 could offer the advantages of a more convenient route of administration for patients with acromegaly and other indications and also a preferential safety profile compared to injections.
Methods
: This First in Human study includes a double-blind, randomized, placebo-controlled, single ascending dose (SAD) part (including an assessm… Show more
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