Abstract:Background:
The term “adrenal androgen” is often used to describe the adrenal-produced androgen precursors, dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). The human adrenal, however, also secretes 11-oxygenated androgens that include 11-hydroxyandrostenedione (11OHA4), 11-ketoandrostenedione (11KA4), 11-hydroxytestosterone (11OHT) and 11-ketotestosterone (11KT), of which 11OHT and 11KT are bioactive. These clinically important steroids have been implicated in diseases of androgen excess, in… Show more
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