“…Globally, as of 16 December 2022 there have been 647,972,911 confirmed cases of COVID-19, including 6,642,832 deaths, and a total of 13,008,560,983 vaccine doses have been administered(https://covid19.who.int). SARS-CoV-2 caused the third viral pandemic of the 21st century, and the third zoonotic coronavirus pandemic outbreak in the past 20 years [1] . SARS-CoV-2 has genetically mutated under genetic evolutionary pressures and will continue to drift mutations.…”