“…The most important message is that the benefits of vaccine administration continue to outweigh risks in terms of overall mortality and GBS incidence ( Abolmaali et al, 2022 ). Recent meta-analysis including 48 publications including 2,110,441,600 participants revealed COVID vaccine related GBS at a rate of 3.09 per 1 million people within 6 weeks of vaccination, higher to that of the influenza vaccine ( Finsterer et al, 2022 ).…”
COVID-19 infection has had a profound impact on society. During the initial phase of the pandemic, there were several suggestions that COVID-19 may lead to acute and protracted neurologic sequelae. For example, peripheral neuropathies exhibited distinctive features as compared to those observed in critical care illness. The peripheral nervous system, lacking the protection afforded by the blood–brain barrier, has been a particular site of sequelae and complications subsequent to COVID-19 infection, including Guillain-Barre syndrome, myasthenia gravis, and small fiber neuropathy. We will discuss these disorders in terms of their clinical manifestations, diagnosis, and treatment as well as the pathophysiology in relation to COVID-19.
“…The most important message is that the benefits of vaccine administration continue to outweigh risks in terms of overall mortality and GBS incidence ( Abolmaali et al, 2022 ). Recent meta-analysis including 48 publications including 2,110,441,600 participants revealed COVID vaccine related GBS at a rate of 3.09 per 1 million people within 6 weeks of vaccination, higher to that of the influenza vaccine ( Finsterer et al, 2022 ).…”
COVID-19 infection has had a profound impact on society. During the initial phase of the pandemic, there were several suggestions that COVID-19 may lead to acute and protracted neurologic sequelae. For example, peripheral neuropathies exhibited distinctive features as compared to those observed in critical care illness. The peripheral nervous system, lacking the protection afforded by the blood–brain barrier, has been a particular site of sequelae and complications subsequent to COVID-19 infection, including Guillain-Barre syndrome, myasthenia gravis, and small fiber neuropathy. We will discuss these disorders in terms of their clinical manifestations, diagnosis, and treatment as well as the pathophysiology in relation to COVID-19.
“…Missing is a discussion about the prevalence of neuro-COVID since introduction of the various anti-SARS-CoV-2 vaccinations. There are indications that, at least for SARS-CoV-2-related Guillain-Barre syndrome, its prevalence has declined since introduction of world-wide vaccination campaigns (3).…”
“…Another musculoskeletal complication of SARS-CoV-2 infections or vaccination that was not discussed in the review article is Guillain-Barre syndrome (GBS). 4 Although neuropathies have been mentioned generally, GBS deserves special attention as it can be complicated by respiratory muscles involvement and may require mechanical ventilation. In addition, involvement of the respiratory muscle in GBS can easily be confused with SARS-CoV-2 pneumonia as both conditions can coexist in the same patient.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.