SARS-CoV-2 universal screening upon adult hospital admission in Southern Israel

Saidel-Odes, Lisa; Shafat, Tali; Nativ, Ronit; Borer, Abraham; Nesher, Lior

doi:10.1016/j.jhin.2021.04.026

Cited by 10 publications

(13 citation statements)

References 9 publications

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“…25 Universal COVID-19 screening for all hospitalized patients is a resource-intensive task, but it could sometimes still play a key role in limiting the spread from the community, given the inseparable connection between healthcare institutions and their neighboring communities. 26 Although the results of COVID-19 screening prior to hospitalization vary with its prevalence, [27][28][29][30][31][32] pre-hospital screening has been widely recommended. 27,28,[30][31][32] However, real-world data on the screening criteria for hospitalized patients remain scarce.…”

Section: Introductionmentioning

confidence: 99%

“…26 Although the results of COVID-19 screening prior to hospitalization vary with its prevalence, [27][28][29][30][31][32] pre-hospital screening has been widely recommended. 27,28,[30][31][32] However, real-world data on the screening criteria for hospitalized patients remain scarce. In this study we aimed to explore whether patients with negative results of pre-hospital screening for COVID-19 who develop fever or pneumonia after admission should be rescreened in a low-prevalence setting.…”

Section: Introductionmentioning

confidence: 99%

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COVID-19 Screening for Hospitalized Patients: The Role of Expanded Hospital Surveillance in a Low Prevalence Setting

Hsu¹,

Liu²,

Tseng³

et al. 2021

JMDH

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Purpose:The COVID-19 pandemic poses a serious threat to healthcare workers and hospitalized patients. Early detection of COVID-19 cases is essential to control the spread in healthcare facilities. However, real-world data on the screening criteria for hospitalized patients remain scarce. We aimed to explore whether patients with negative results of prehospital screening for COVID-19 should be rescreened after admission in a low-prevalence (less than 3% of the world average) setting. Patients and Methods:We retrospectively included patients in central Taiwan who were negative at the first screening but were newly diagnosed with pneumonia or had a body temperature above 38 degrees Celsius during their hospitalization. Each patient might be included as an eligible case several times, and the proportions of cases who were rescreened for COVID-19 and those diagnosed with COVID-19 were calculated. A logistic regression model was constructed to identify factors associated with rescreening. Reverse transcriptionpolymerase chain reaction tests were used to confirm the diagnosis of COVID-19. Results: A total of 3549 cases eligible for COVID-19 rescreening were included. There were 242 cases (6.8%) who received rescreening. In the multivariable analysis, cases aged 75 years or older, those with potential exposure to SARS-CoV-2, or patients visiting specific departments, such as the Cardiovascular Center and Department of Neurology, were more likely to be rescreened. None was diagnosed with COVID-19 after rescreening. There was no known cluster infection outbreak in the hospital or in the local community during the study period and in the following two months. Conclusion:In Taiwan, a country with a low COVID-19 prevalence, it was deemed safe to rescreen only high-risk hospitalized patients. This strategy was effective and reduced unnecessary costs.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

COVID-19 Screening for Hospitalized Patients: The Role of Expanded Hospital Surveillance in a Low Prevalence Setting

Hsu¹,

Liu²,

Tseng³

et al. 2021

JMDH

View full text Add to dashboard Cite

show abstract

“…During the study period, SARS‐CoV‐2 PCR testing was available by self‐referral to all HM patients whenever deemed necessary regardless of treatment and as part of universal screening upon hospital admission. 8 We identified the Omicron variant by either sequencing or when compatible mutations were found in the S gene by Allplex™ SARS‐CoV‐2 Master Assay (Seegene, Seoul, South Korea). Follow‐up continued until 1 April 1 2022 or death.…”

mentioning

confidence: 99%

Treatment with obinutuzumab leads to worse outcomes in haematological patients diagnosed with Omicron variant COVID‐19

et al. 2022

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“…This approach could have swayed results toward a seemingly larger number of asymptomatic cases. 16 In our study, even though symptom determination was based solely on provider input, providers ordering admission COVID-19 tests had been educated to label and categorize patients with any potential COVID symptoms as symptomatic. However, even with adequate education, the use of provider determination of symptom determination is imperfect.…”

Section: Discussionmentioning

confidence: 99%

Universal admission laboratory screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) asymptomatic infection across a large health system

Cihlar

Harris

Wright

et al. 2022

Infect. Control Hosp. Epidemiol.

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Background: Admission laboratory screening for asymptomatic coronavirus disease 2019 (COVID-19) has been utilized to mitigate healthcare-associated severe acute respiratory coronavirus virus 2 (SARS-CoV-2) transmission. An understanding of the impact of such testing across a variety of patient populations is needed. Methods: SARS-CoV-2 nucleic acid amplification admission testing results for all asymptomatic patients across 4 distinct inpatient facilities between April 20, 2020, and June 14, 2021, were analyzed. Positivity rates and the number needed to test (NNT) to identify 1 asymptomatic infected patient were calculated. Admission results were compared to COVID-19 community incidence rates for the system’s surrounding metropolitan service area. Using a national survey of hospital epidemiologists, a clinically meaningful NNT of 1:100 was identified. Results: In total, 51,187 tests were collected (positivity rate, 1.8%). During periods of high transmission, the NNT met the clinically relevant threshold in all populations. The NNT approached or met the threshold for most locations during periods of lower transmission. For all transmission levels, the NNT for fully vaccinated patients did not meet the threshold. Conclusions: Implementing an asymptomatic patient admission testing program can provide clinically relevant data based on the NNT, even during periods of lower transmission and among different patient populations. Limiting admission testing to non–fully vaccinated patients during periods of lower transmission may be a strategy to address resource concerns around this practice. Although the impact of such testing on healthcare-associated COVID-19 among patients and healthcare workers could not be clearly determined, these data provide important information as facilities weigh the costs and benefits of such testing.

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SARS-CoV-2 universal screening upon adult hospital admission in Southern Israel

Cited by 10 publications

References 9 publications

COVID-19 Screening for Hospitalized Patients: The Role of Expanded Hospital Surveillance in a Low Prevalence Setting

COVID-19 Screening for Hospitalized Patients: The Role of Expanded Hospital Surveillance in a Low Prevalence Setting

Treatment with obinutuzumab leads to worse outcomes in haematological patients diagnosed with Omicron variant COVID‐19

Universal admission laboratory screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) asymptomatic infection across a large health system

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