SARS-CoV-2 seroprevalence and determinants for salivary seropositivity among pupils and school staff: a prospective cohort study

Merckx, Joanna; Callies, Milena; Kabouche, Ines; Desombere, Isabelle; Duysburgh, Els; Roelants, Mathieu

doi:10.1017/s0950268823000584

Cited by 1 publication

(1 citation statement)

References 21 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…and an important rise in SARS-CoV-2 infections compared to 2020. Indeed, SARS-CoV-2 seroprevalence in Belgian pupils rose steeply from 24% in June 2021 to 60% in December 2021 with more than half of these pupils infected during the fourth pandemic wave which was dominated by the delta variant [35]. SARS-CoV-2 has so far not been described as an important childhood wheeze trigger except in the report of Ruano et al [36] describing an increased use of reliever therapy in a group of asthmatic children with probable COVID-19.…”

Section: Discussionmentioning

confidence: 99%

Wheezing Episodes in Children Before and After the Onset of the COVID-19 Pandemic in Brussels

Delporte,

Bruwaene,

Bruffaerts

et al. 2024

Preprint

View full text Add to dashboard Cite

Purpose: Studies have demonstrated important changes in the seasonality of pediatric respiratory illnesses since the onset of the COVID-19 pandemic. The aim of this study was to describe the epidemiology of childhood wheezing episodes before and after the start of the COVID-19 pandemic in relation to their potentially associated environmental triggers. Methods: Files of all children treated with salbutamol for a wheezing episode in September and October 2019, 2020 and 2021 were retrospectively reviewed. Infection epidemiology, daily concentrations of air pollutants (NO2, O3, PM10 and PM2.5) and fungal spores were collected over the same time period. Results: In 2021, 298 episodes of wheezing were observed compared to 111 in 2020 and 86 in 2019 (p<0.001). Compared to 2019, children with wheezing in 2021 were significantly older (p<0.001), less likely to have a history of recurrent wheezing (p<0.001) and required less hospitalization (p=0.034). Adenovirus and SARS-CoV-2 were more prevalent in 2021 as compared to 2019 (p<0.001). The concentration of PM10, PM2.5 and O3 was higher in 2021, as compared to both 2019 and 2020 (p<0.001) while the concentration of NO2 and airborne spores was lower in 2021 compared to 2019 (p<0.0001). Conclusion: A threefold increase in wheezing episodes was observed in the autumn post-COVID (2021) compared to pre-COVID (2019) together with a significant increase in some viruses and most air pollutants. We hypothesize that this abnormal surge may be related to the release of restrictions with rapid spread of viruses in children who were exposed to high levels of air pollution.

show abstract

Section: Discussionmentioning

confidence: 99%