SARS-CoV-2 RNA Detected in Abdominal Insufflation Samples During Laparoscopic Surgery

Badani, Ketan K.; Okhawere, Kennedy; Chen, Tina; Korn, Talia G; Razdan, Shirin; Meilika, Kirolos; Wilson, Michael P.; Tomy, Tara; Üçpınar, Burak; Kyprianou, Natasha; Dogra, Navneet

doi:10.1016/j.eururo.2021.10.034

Cited by 4 publications

(5 citation statements)

References 3 publications

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“… [22] Subsequently, SARS-CoV-2 has been identified in abdominal insufflation samples, but there have been no documented cases of viral transmission from surgical aerosolization. [23] Whether urologists performed a higher rate of open approaches due to the theoretical risk is unknown. There has been a documented trend towards increased MIS approaches to urologic oncology.…”

Section: Discussionmentioning

confidence: 99%

Impact of COVID-19 on Society of Urologic Oncology fellowship operative volumes

Daily

Koenig²,

Kord

et al. 2022

Urologic Oncology: Seminars and Original Investigations

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Section: Discussionmentioning

confidence: 99%

Impact of COVID-19 on Society of Urologic Oncology fellowship operative volumes

Daily

Koenig²,

Kord

et al. 2022

Urologic Oncology: Seminars and Original Investigations

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“…The presence of the SARS‐CoV2 have been identified in surgical smoke during laparoscopy leading to the recommendation to use smoke aspiration and filtration to avoid air contamination in the surgical room. Controversy surrounding how COVID‐19 is transmitted and what interventions are needed to control the pandemic has revealed a critical need to better understand the airborne transmission pathway of respiratory viruses and to propose measures for prevention of transmission 4,5 . Not surprisingly, SARS‐CoV‐2 RNA has been identified in air samples from rooms or wards housing unmasked patients with COVID‐19 6 .…”

Section: Introductionmentioning

confidence: 99%

“…Controversy surrounding how COVID‐19 is transmitted and what interventions are needed to control the pandemic has revealed a critical need to better understand the airborne transmission pathway of respiratory viruses and to propose measures for prevention of transmission. 4 , 5 Not surprisingly, SARS‐CoV‐2 RNA has been identified in air samples from rooms or wards housing unmasked patients with COVID‐19. 6 Meta‐analysis suggested that there is association between face mask use and reduction of COVID‐19 paving for the impact of infected respiratory droplets.…”

Section: Introductionmentioning

confidence: 99%

Airborne transmission of SARS‐Cov2: What consequences for digestive endoscopy?

et al. 2023

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The SARS-Cov-2 disease disrupted essential hospital procedures, such as gastrointestinal (GI) endoscopy, due to concerns about air transmission and the risk of exposing health care workers. With the spread of the pandemic, air transmission was considered as the main source of SARS-Cov2 transmission. This raised the problem of transmission by aerosolization of viral particles in operating rooms as well as endoscopy units. This is in line with the known airborne transmission of many other respiratory viruses. The risk of SARS-Cov-2 transmission during GI endoscopy was initially reduced by controlled measures, involving personal protections (mask…), restricted access to endoscopy rooms, and detection of infected patients. Gastrointestinal endoscopy generates aerosols, which may carry viruses. In addition, the endoscopy system may facilitate the diffusion of virus particles or fomites considering the forced-air cooling system used to maintain a stable temperature inside the box (25°C). The volume of air that goes through the light source box is high (240-300 m 3 for a 1-h period). Moreover, the light system contains an air pump to inflate air inside the gut lumen. In order to isolate people from hazard, different levels of protection and solutions to avoid airborne transmission of microorganisms should be proposed, such as the reinforcement of personal protective equipment, the change in the way people work and engineering control of the risk.

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“…Non-invasive methods contribute to the diagnosis of kidney cancers and may help facilitate early detection of aggressive tumors [128]. Recently, abdominal insufflation samples during laparoscopic surgery were analyzed non-invasively [129]. Furthermore, early screening and distinguishing between benign and malignant masses may help improve survival and avoid unnecessary surgery [74,122,130].…”

Section: Introductionmentioning

confidence: 99%

Clinical Significance of Extracellular Vesicles in Prostate and Renal Cancer

Chen,

Mihalopoulos,

Zuluaga

et al. 2023

IJMS

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Extracellular vesicles (EVs)—including apoptotic bodies, microvesicles, and exosomes—are released by almost all cell types and contain molecular footprints from their cell of origin, including lipids, proteins, metabolites, RNA, and DNA. They have been successfully isolated from blood, urine, semen, and other body fluids. In this review, we discuss the current understanding of the predictive value of EVs in prostate and renal cancer. We also describe the findings supporting the use of EVs from liquid biopsies in stratifying high-risk prostate/kidney cancer and advanced disease, such as castration-resistant (CRPC) and neuroendocrine prostate cancer (NEPC) as well as metastatic renal cell carcinoma (RCC). Assays based on EVs isolated from urine and blood have the potential to serve as highly sensitive diagnostic studies as well as predictive measures of tumor recurrence in patients with prostate and renal cancers. Overall, we discuss the biogenesis, isolation, liquid-biopsy, and therapeutic applications of EVs in CRPC, NEPC, and RCC.

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SARS-CoV-2 RNA Detected in Abdominal Insufflation Samples During Laparoscopic Surgery

Cited by 4 publications

References 3 publications

Impact of COVID-19 on Society of Urologic Oncology fellowship operative volumes

Impact of COVID-19 on Society of Urologic Oncology fellowship operative volumes

Airborne transmission of SARS‐Cov2: What consequences for digestive endoscopy?

Clinical Significance of Extracellular Vesicles in Prostate and Renal Cancer

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