SARS-CoV-2 in eight municipalities of the Colombian tropics: high immunity, clinical and sociodemographic outcomes

Garay, Evelin; Serrano-Coll, Héctor; Rivero, Ricardo; Gastelbondo, Bertha; Faccini-Martínez, Álvaro A.; Berrocal, José; Perez, Alejandra Isabel; Badillo, María Luisa Ordoñez; Martínez-Bravo, Caty; Botero, Yesica; Arrieta, Germán; Calderón, Alfonso; Galeano, Ketty; López, Yesica; Miranda, Jorge; Guzmán, Camilo; Contreras, Verónica; Arosemena, Alejandra; Contreras, Héctor; Brango-Tarra, Eimi; Oviedo, Misael; Máttar, Salim

doi:10.1093/trstmh/trab094

Cited by 8 publications

(5 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have shown that SARS-CoV-2 infection-induced seroprevalence between January and December 2020 was independently associated with low socio-economic rank. Similar findings were also observed in the United States [ 10 , 20 ], in Mexico [ 14 ], in a study performed in Colombia among children [ 21 ], and in a previous sero-epidemiological survey we conducted among children between January 2020 and March 2021 in Israel [ 22 ]. SARS-CoV-2 is transmitted from person to person by exposure to infected respiratory fluids.…”

Section: Discussionsupporting

confidence: 87%

Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020–July 2021

et al. 2022

View full text Add to dashboard Cite

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in Israel in February 2020 and spread from then. In December 2020, the FDA approved an emergency use authorization of the Pfizer-BioNTech vaccine, and on 20 December, an immunization campaign began among adults in Israel. We characterized seropositivity for IgG anti-spike antibodies against SARS-CoV-2 between January 2020 and July 2021, before and after the introduction of the vaccine in Israel among adults. We tested 9520 serum samples, collected between January 2020 and July 2021. Between January and August 2020, seropositivity rates were lower than 5.0%; this rate increased from September 2020 (6.3%) to April 2021 (84.9%) and reached 79.1% in July 2021. Between January and December 2020, low socio-economic rank was an independent, significant correlate for seropositivity. Between January and July 2021, the 40.00–64.99-year-old age group, Jews and others, and residents of the Northern district were significantly more likely to be seropositive. Our findings indicate a slow, non-significant increase in the seropositivity rate to SARS-CoV-2 between January and December 2020. Following the introduction of the Pfizer-BioNTech vaccine in Israel, a significant increase in seropositivity was observed from January until April 2021, with stable rates thereafter, up to July 2021.

show abstract

Section: Discussionsupporting

confidence: 87%

Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020–July 2021

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Therefore, it would be necessary to analyze this topic more carefully. In the indigenous and other populations, we did not find evidence that the SARS-CoV-2 infection rate is affected by the sex variable [ 6 ].…”

Section: Discussionmentioning

confidence: 96%

“…Madrid) was used, which uses a recombinant N protein for SARS-CoV-2. The test measures totaled IgG, IgM, and IgA antibodies and were previously validated in our laboratory [ 6 ]. Analysis of data.…”

Section: Methodsmentioning

confidence: 99%

High Prevalence of SARS-CoV-2 in an Indigenous Community of the Colombian Amazon Region

Serrano-Coll

Miller

Hamen³

et al. 2021

TropicalMed

Self Cite

View full text Add to dashboard Cite

Introduction. COVID-19 is a pathology caused by the SARS-CoV-2 virus. The World Health Organization (WHO) has reported more than 225 million cases and 4.5 million deaths worldwide. Objective: To describe the seropositivity, spatial distribution, and clinical and sociodemographic variables of SARS-CoV-2 in a community of the Colombian Amazon region. Methods. In December 2020, a cross-sectional observational study was carried out in a population located in the Colombian Amazon in the municipality of Mitú. Sociodemographic and clinical data were taken. Besides, 589 blood samples were taken, and an antibody detection was carried out with an ELISA and a recombinant protein N antigen of SARS-CoV-2. Results. A seropositivity of 57.6% was observed. The highest proportion of the infection is located in inter-municipal transport zones. The bivariate analysis did not show differences in the SARS-CoV-2 infection rate concerning the variables sex, age range, and the presence of comorbidities (p > 0.05). The bivariate and multivariate analysis showed that being symptomatic and presenting neurological manifestations of the upper respiratory tract are clinical variables associated with SARS-CoV-2 infection (p < 0.05). One of the causes of this virus’s high spread in this community could be that 53.3% of the people were asymptomatic. Conclusions. Our data showed a high burden and transmission of SARS-CoV-2 in the indigenous community. This could be linked to cultural behaviors and the high infection rate in asymptomatic patients.

show abstract

“…Another study reported high seropositivity for COVID-19 in people from the department of Córdoba (40.8%). 21 Altogether a high density of pets and a high density of people with COVID-19 could increase the risk of transmission of SARS-CoV-2 to domestic animals.…”

Section: Discussionmentioning

confidence: 99%

First report and genome sequencing of SARS-CoV-2 in a cat (Felis catus) in Colombia

Botero

Ramírez

Serrano-Coll

et al. 2022

Mem. Inst. Oswaldo Cruz

Self Cite

View full text Add to dashboard Cite

BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus of zoonotic origin that can bind to ACE2 receptors on the cells of many wild and domestic mammals. Studies have shown that the virus can circulate among animals mutate, lead to animal-to-human zoonotic jump, and further onward spread between humans. Infection in pets is unusual, and there are few human-to-pet transmission reports worldwide. OBJECTIVE To describe the SARS-CoV-2 infection in a domestic animal in Córdoba, Colombian Caribbean region. METHODS A cross-sectional molecular surveillance study was carried out, oral and rectal swabs were taken from cats and dogs living with people diagnosed with coronavirus disease 2019 (COVID-19). RESULTS SARS-CoV-2 was found in a cat living with a person with COVID-19. Genome sequencing showed that the B.1.111 lineage caused the infection in the cat. The owner’s sample could not be sequenced. The lineage is predominant in Colombia, and this variant is characterised by the presence of the D614D and Q57H mutation. CONCLUSION The present work is the first report of an infected cat with SARS-CoV-2 with whole-genome sequencing in Colombia. It highlights the importance of detecting SARS-CoV-2 mutations that could promote the transmissibility of this new coronavirus. There is still a significant information gap on human-to-cat-to-human infection; we encourage self-isolation measures between COVID-19 patients and companion animals. The findings of this study give a preliminary view of the current panorama of SARS-CoV-2 infection in animals in Colombia.

show abstract

SARS-CoV-2 in eight municipalities of the Colombian tropics: high immunity, clinical and sociodemographic outcomes

Cited by 8 publications

References 21 publications

Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020–July 2021

Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020–July 2021

High Prevalence of SARS-CoV-2 in an Indigenous Community of the Colombian Amazon Region

First report and genome sequencing of SARS-CoV-2 in a cat (Felis catus) in Colombia

Contact Info

Product

Resources

About