SARS-CoV-2 and COVID-19: From Crisis to Solution

Abstract

The global impact of the COVID-19 pandemic persists, causing significant harm. Extensive evidence indicates that even mild infections and reinfections can result in symptomatic and subclinical health damage, disability, and persistent infection. Vascular impacts, neurotropism, and immune dysregulation lead to impaired organ function, increased morbidity and mortality, compromised work productivity, and a decline in overall health and quality of life. The uncontrolled spread of the virus is accelerating its evolution, outpacing the effectiveness of vaccines, treatments, and immune system adaptation. This preventable disease and others magnified by immune dysfunction are driving staff shortages, supply chain disruptions, and overwhelming healthcare systems. Despite the dire nature of the current conditions, knowledge and means are present to solve these problems. We present a science-based strategy for confronting the ongoing pandemic, including reducing airborne transmission through clean indoor air programs comparable with historical clean water programs. Public and professional education on the implications of repeated SARS-Cov-2 infections and utilizing known preventive measures can dramatically reduce transmission, which in turn reduces the rate of new variant introduction and strengthens the effectiveness of vaccines and treatments. It is essential to restore the prioritization of health and safety in healthcare and society.