Sarcomatoid Variant of Urothelial Carcinoma of the Renal Pelvis with Inferior Vena Cava Tumour Thrombus: A Case Report and Literature Review

Rashid, Sameera; Akhtar, Mohammed

doi:10.1155/2018/1837510

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…The sarcomatoid variant of urothelial carcinoma is rare, but has been reported in the urinary bladder [ 5 ], bladder diverticulum [ 6 ], ureter [ 7 ], renal pelvis [ 8 ], and urethra [ 9 ]. As far as we know, this is the first case report of sarcomatoid UC arising from a urethral diverticulum.…”

Section: Discussionmentioning

confidence: 99%

Sarcomatoid urothelial carcinoma arising in the female urethral diverticulum

Park

2021

J Pathol Transl Med

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A sarcomatoid variant of urothelial carcinoma in the female urethral diverticulum has not been reported previously. A 66-year-old woman suffering from dysuria presented with a huge urethral mass invading the urinary bladder and vagina. Histopathological examination of the resected specimen revealed predominantly undifferentiated pleomorphic sarcoma with sclerosis. Only a small portion of conventional urothelial carcinoma was identified around the urethral diverticulum, which contained glandular epithelium and villous adenoma. The patient showed rapid systemic recurrence and resistance to immune checkpoint inhibitor therapy despite high expression of programmed cell death ligand-1. We report the first case of urethral diverticular carcinoma with sarcomatoid features.

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Section: Discussionmentioning

confidence: 99%

Sarcomatoid urothelial carcinoma arising in the female urethral diverticulum

Park

2021

J Pathol Transl Med

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“…The surgical management does not differ based on UTUC versus renal cell carcinoma primary; however, the paucity of cases restricts extensive review of various surgical techniques (64-68). Variant histology is not common, but when present, sarcomatoid differentiation is most commonly seen, although it is less common in general (69)(70)(71).…”

Section: Adrenal Managementmentioning

confidence: 99%

The nephroureterectomy: a review of technique and current controversies

2020

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The nephroureterectomy surgery has been utilized for more than 100 years. In 1898, Dentu and Albarran described the first nephroureterectomy, which only involved removing a portion of the ureter (1). Kimball and Ferris subsequently noted tumor recurrences in the remaining distal portion of the ureter, and expressed the importance of resecting the entire ureter; from renal pelvis to the intramural ureter (2). In 1991 the first laparoscopic nephroureterectomy (LNU) was reported by Clayman (3). The first report of the use of a surgical robot for nephrectomy was reported in 2001, followed by the first robotic assisted heminephroureterectomy in 2004, although this was performed for recurrent infections and incontinence due to ectopic ureters, not upper tract urothelial carcinoma (UTUC) (4,5). In 2006, Nanigian et al. subsequently reported the first robotic-assisted laparoscopic nephroureterectomy (RANU) (6,7). For high-grade UTUC, radical nephroureterectomy has been and still is the standard of care. In this review, we describe the radical nephroureterectomy, specific nuances, areas of debate, outcomes, and the future of the procedure. Description of techniqueNephroureterectomy is best categorized into two parts of the surgery: (I) radical nephrectomy and (II) distal ureterectomy (8). Each of these parts can be performed with

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Sarcomatoid variant of urothelial carcinoma of renal pelvis with direct invasion of the pancreas and descending colon

et al. 2022

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Introduction Sarcomatoid variant of urothelial carcinoma infiltrates the perimeter and occurs occasionally. However, there are only few case reports. Case presentation A left renal tumor was incidentally detected in a 75‐year‐old woman and protruded outside the kidney, infiltrating the pancreatic tail and spleen. Tumor invasion was observed in the adjacent organs; therefore, the left kidney, pancreatic tail, spleen, and, descending colon were resected. Histopathological examination revealed a sarcomatoid variant of invasive urothelial carcinoma. She received two cycles of gemcitabine and carboplatin combination chemotherapy but succumbed to the disease after 5 months. Conclusion Sarcomatoid variant of urothelial carcinoma is rare, with aggressive malignancy. The diagnosis was difficult and required surgery. This is the first case of a sarcomatoid variant of urothelial carcinoma with direct invasion into the pancreas and descending colon.

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Sarcomatoid Variant of Urothelial Carcinoma of the Renal Pelvis with Inferior Vena Cava Tumour Thrombus: A Case Report and Literature Review

Cited by 5 publications

References 19 publications

Sarcomatoid urothelial carcinoma arising in the female urethral diverticulum

Sarcomatoid urothelial carcinoma arising in the female urethral diverticulum

The nephroureterectomy: a review of technique and current controversies

Sarcomatoid variant of urothelial carcinoma of renal pelvis with direct invasion of the pancreas and descending colon

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