Sarcomatoid Squamous Cell Carcinoma of Alveolus: A Rare Case Presentation

Abstract

To describe a rare case of sarcomatoid squamous cell carcinoma of alveolus. A 53-year-old female with complaints of non-healing ulcerative growth over the left side of the hard palate, which was associated with pain for two months. She underwent extraction and a Histo-pathological examination of teeth with attached soft tissue was suggestive of Sarcomatoid Carcinoma. The patient underwent Left infrastructure maxillectomy with wide local excision with left modified radical neck dissection type II. Histopathology showed lympho-vascular infiltration and perineural infiltration. All margins were free. Out of 8 lymph nodes that were dissected, 1 showed metastatic disease. The patient received adjuvant concurrent radio-chemotherapy 66Gy in 33 fractions (2Gy/day) in two phases along with weekly Injection Cisplatin 40 mg/m2. Sarcomatoid squamous carcinoma is a rare and uncommon variant of squamous cell carcinoma. It is aggressive in nature and shows early recurrence and metastasis. Thus, associated with a poor prognosis. There is no defined treatment protocol for this variant. We have discussed a case of sarcomatoid carcinoma of the alveolus that was operated and followed by adjuvant chemo-radiotherapy.