Sarcomatoid Salivary Duct Carcinoma of the Submandibular Gland

Management of sarcomatoid salivary duct carcinoma of the submandibular gland duct with coexisting seropositive human immunodeficiency virus

“…Due to the rarity of this disease, there is no universal consensus on management; however, surgery was performed in all previously reported cases. [3][4][5][6] There are no data to support the routine use of radiotherapy. We think that postoperative radiotherapy would be wise in cases with adverse prognostic features (such as locally advanced disease, close or positive margins, multiple lymph nodes, extra capsular extension, perineural invasion, and lymphovascular space invasion).…”

“…1 Submandibular gland sarcomatoid salivary duct carcinoma of Wharton's duct has been reported in a few cases. [2][3][4][5][6] However, it has never been reported in a patient with coexisting human immunodeficiency virus (HIV). Given the rarity of these malignancies, treatments are non-evidence based and are extrapolated from experiences of other head and neck malignancies of similar histology and/or location.…”