Sarcomatoid salivary duct carcinoma of minor salivary gland: A rare case

Thamilselvi, R; Subramaniam, PM; Shivarudrappa, A S; Venugeethan, A; Sinha, Pammy

doi:10.4103/0377-4929.72102

Cited by 9 publications

(8 citation statements)

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“…2,[5][6][7][8][9][10][11] Additionally, SDC is characterized by its resemblance to breast ductal carcinoma. Therefore, metastatic SDC and metastatic breast ductal carcinoma must be excluded before a diagnosis of primary pulmonary SDC.…”

Section: Discussionmentioning

confidence: 99%

Primary High-Grade Salivary-Type Duct Carcinoma of the Lung

et al. 2014

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Primary salivary gland-type lung cancers are a rare group of tumors. When they do occur, the most common type is adenoid cystic carcinoma, followed by mucoepidermoid carcinoma. Primary high-grade salivary-type duct carcinoma (HGSDC) arising in the lung has not been described. We report a case of primary pulmonary HGSDC in a 55-year-old woman who was referred to our hospital for a suspicious lung tumor. The chest computed tomography revealed a solid mass in the left upper lobe. A lobectomy was performed afterward, and the mass was a primary lung HGSDC. To the best of our knowledge, HGSDC arising in the lung has not been reported previously.

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Section: Discussionmentioning

confidence: 99%

Primary High-Grade Salivary-Type Duct Carcinoma of the Lung

et al. 2014

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“…Intraoral SDC is a rare malignant neoplasm, accounting for less than 2% of all malignant minor salivary gland tumors of the oral cavity as reported in a recent series. [ 4 ] To the best of our knowledge, based on evidence in the literature, only 35 cases of SDC have occurred in the minor salivary glands, including the present case[ 1 2 4 5 7 8 9 10 11 12 ] The male to female ratio reported in these studies is approximately 2:1. The patients ranged from 23-80 years of age, which suggest that, like parotid gland SDC, minor salivary gland SDC occurs primarily in elderly men.…”

Section: Discussionmentioning

confidence: 74%

“…Although it is difficult to determine the predominant location of SDC in the minor salivary glands because of the limited number of cases, they occurred most frequently on the palate (20 cases) followed by buccal mucosa/vestibule (4 cases), the tongue (2 cases), the maxilla (4 cases), the mandible (1) and the upper lip (1), floor of mouth (1), hypopharynx (1), sinonasal tract (1). [ 1 2 4 5 7 8 9 10 11 12 ]…”

Section: Discussionmentioning

confidence: 99%

Intraoral salivary duct carcinoma: A case report and a brief review

Acharya

Padmini

Koneru

et al. 2014

J Oral Maxillofac Pathol

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Salivary duct carcinoma (SDC) is a rare, extremely aggressive malignancy arising in the ductal epithelium of the salivary glands. SDC occurs almost exclusively in the major salivary glands with parotid gland predominantly affected. Only isolated cases involving minor salivary glands have been reported in the literature. We report an unusual case of extensive SDC occupying the right cheek and the maxillary sinus, possibly arising from the minor glands of the buccal mucosa or from the mixed glands of the maxillary sinus in a 71-year-old man. The case was subjected to a panel of immunohistochemical markers like pan cytokeratin, low molecular weight cytokeratin (LMW CK), high molecular weight cytokeratin (HMW CK), CK 7, CK 20, CD 117, carcinoembryonic antigen (CEA), S-100, p63, Gross cystic disease fluid protein (GCDFP-15) and estrogen receptor (ER) to arrive at a definitive diagnosis.

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“…Griffith et al 73 list several malignant and benign entities in their classification of oncocytoid cells including SDC. In addition, SDC has been confused with PA in several studies 14,27 . Khurana et al 24 warn of the danger of mistaking hyalinized foci sampled by FNA in SDC cases for the chondromyxoid matrix seen in PA.…”

Section: Discussionmentioning

confidence: 99%

“…However, a profusion of reports regarding both classic and variant histopathology of SDC coupled with the more frequent application of androgen receptor (AR) immunohistochemical (IHC) staining has led to an increased precise recognition of this neoplasm. [2][3][4][5] Although the fine-needle aspiration (FNA) cytopathology of SDC has been the subject of numerous articles, these articles have consisted primarily of single examples, [6][7][8][9][10][11][12][13][14][15][16][17][18] or those comprising 2 to 10 cases. [19][20][21][22][23][24][25][26][27] Only a handful of series with more than 10 examples have been published [28][29][30] with the largest consisting of 27 cases.…”

Section: Introductionmentioning

confidence: 99%

Salivary duct carcinoma: A report of 70 FNA cases and review of the literature

Wakely

2022

Cancer Cytopathology

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BACKGROUND:Although usually recognized as malignant, fine-needle aspiration (FNA) biopsy of salivary duct carcinoma (SDC) has been confused with other primary salivary gland (SG) neoplasms. This article undertook an analysis of a large collection of SDC FNA cases to assess diagnostic accuracy, specificity, and cytopathology. METHODS: Cytopathology files were searched for SDC with histopathologic validation. FNA biopsy smears were performed using standard techniques. RESULTS:Seventy cases from 56 patients (M:F, 1.9:1; age range, 26-92 years; mean age, 65 years) met inclusion criteria. All had tissue confirmation of SDC. FNA sites included: parotid gland (42, 60% cases), neck (10), submandibular gland (7), pre-/ post-auricular area (5), face/cheek (3), mediastinal lymph nodes (2), and clavicle (1). Aspirates were from primary (52, 74%), metastatic (12, 17%), and locally recurrent (6, 9%) neoplasms. FNA diagnoses included: SDC (19, 27%), favor/suspicious for SDC (7, 10%), high-grade carcinoma (11), adenocarcinoma ( 9), carcinoma ( 6), malignant (6), SG neoplasm (5), atypia (3), SDC versus another malignancy (2), and pleomorphic adenoma (2). Large polygonal cells in groups and single forms showed cribriforming, variable necrosis, pseudopapillae, and oncocytic change. Androgen receptor staining was positive in all cases.CONCLUSIONS: FNA biopsy is accurate and reliable in classifying SDC as a malignant neoplasm, but much less so for identification as a specific tumor type. Using the Milan system, 86% of aspirates were classified as either malignant or suspicious for malignancy. A recurring pitfall includes sampling error in cases of SDC ex pleomorphic adenoma. Cancer Cytopathol 2022;130:595-608.

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Sarcomatoid salivary duct carcinoma of minor salivary gland: A rare case

Cited by 9 publications

References 0 publications

Primary High-Grade Salivary-Type Duct Carcinoma of the Lung

Primary High-Grade Salivary-Type Duct Carcinoma of the Lung

Intraoral salivary duct carcinoma: A case report and a brief review

Salivary duct carcinoma: A report of 70 FNA cases and review of the literature

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