Sarcoma of the prostate

Abstract

The experience at the University of Iowa Hospitals with 12 patients having sarcoma of the prostate is described. Although the total number of patients is small, two distinct groups can be identified. The infants, children, and young adults presenting with this malignancy had a very poor survival regardless of the therapy administered. However, the older men have generally done well, surviving several years following therapy for the relief of lower urinary tract obstruction. The longest surviving patient was treated by transurethral prostectomy followed by transperineal instillation of radioactive gold. A program of combination therapy utilizing surgery, external irradiation, and triple chemotherapy is suggested for use in children and young adults with prostatic sarcoma.

Imaging appearance of sarcomas of the prostate

“…Sarcomas of the prostate are rare tumours, accounting for 0.1–0.2% of all primary prostatic neoplasms [ 1 , 2 ] . Rhabdomyosarcomas are the most common form, accounting for 42% of prostate sarcomas and occur primarily in children and adolescents [ 3 , 4 ] .…”

“…Rhabdomyosarcomas are the most common form, accounting for 42% of prostate sarcomas and occur primarily in children and adolescents [ 3 , 4 ] . Leiomyosarcomas represent 25% of all prostate sarcomas and are more likely to occur in older men [ 2 , 5 ] . Other subtypes are rarer.…”

Leitlinien zur Therapie von Prostatakarzinomen Im Auftrag der Deutschen Krebsgesellschaft und ihrer wissenschaftlichen Arbeitsgemeinschaften, der Deutschen Krebshilfe und der Deutschen Gesellschaft für Urologie und in Kooperation mit nachstehend angeführten wissenschaftlichen Fachgesellschaften, der Arbeitsgemeinschaft Deutscher Tumorzentren sowie dem Berufsverband Deutscher Urologen

“…Sehr selten finden sich Angiosarkome, Fibrosarkome und maligne Schwannome. Beschrieben ist die radikale Tumorentfernung mit anschließender adjuvanter Polychemotherapie, beim Leiomyosarkom mit adjuvanter Radiotherapie [72,96,18,82]. Bei all diesen seltenen Tumoren steht ein einheitliches Therapiekonzept nicht zur Verfügung [74,106,45,117].…”

CT Imaging Findings of Metastatic Spindle Cell Sarcoma of Prostate: A Case Report and Review of the Literature

“…Other symptoms include tenesmus, pain and hematuria from invasion of the bladder floor and urethra. Sarcomas of the prostate includefor 0.1-0.2% of all primary prostatic neoplasms [1][2][3]. Rhabdomyosarcomas account for 42% of prostate sarcomas and leiomyosarcomas represent 25% of all prostate sarcomas [4,5].…”