Sarcoma of the Fallopian Tube

Blaikley, J. B.

doi:10.1111/j.1471-0528.1973.tb16065.x

Cited by 6 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since the first report on a primary fallopiantubesarcomabyEmilSengerin1886 [2],only35pri-maryuterinetubesarcomashavebeendocumented [3][4][5][6][7][8].Including the present case, 19 of the fallopian tube sarcomas fulfilled the histological criteria for leiomyosarcoma [9,10].…”

Section: Introductionmentioning

confidence: 97%

Primary Metastatic Leiomyosarcoma of the Fallopian Tube: A Rare Case Report

Jacobs¹,

Zemzoum²,

Kremer

et al. 2010

Oncol Res Treat

View full text Add to dashboard Cite

Background: Leiomyosarcoma of the fallopian tube is an extremely unusual gynecologic neoplasm. Since 1886, only 19 of about 35 sarcomas of the fallopian tube have been identified as leiomyosarcomas. As such, clinical diagnosis and therapy management are difficult. Case Report: We report on the case of a 59-year-old woman with leiomyosarcoma of the fallopian tube and liver metas-tases at the time of diagnosis. After initial tumor debulk-ing, she received palliative chemotherapy with gemcitabine 900 mg/m² (d1+8) and docetaxel 100 mg/m² (d8) (q21). For additional bone metastases, she started local radiation plus bisphosphonates (q28). After 2 cycles of chemotherapy, the disease progressed, and the patient died within 8 months of diagnosis. A review of the literature is given. Conclusions: Primary metastatic leiomy-osarcoma of the fallopian tube is a progressive disease with limited therapy options. For better prognostic evaluation and disease management in such rare cases, it is important to report and compare more cases regarding course of disease and outcome.

show abstract

Section: Introductionmentioning

confidence: 97%

Primary Metastatic Leiomyosarcoma of the Fallopian Tube: A Rare Case Report

Jacobs¹,

Zemzoum²,

Kremer

et al. 2010

Oncol Res Treat

View full text Add to dashboard Cite

show abstract

“…Blarkley [52] described a patient who developed bilateral pulmonarymetastases19yearspostoperatively.Ofnote,after pulmonary irradiation, she remained free of disease for at least5years.…”

Section: Primary Leiomyosarcomamentioning

confidence: 99%

“…All recurrences usually occur within 2 years of diagnosis, although distant metastases may also appeardecadeslater [52].…”

Section: Primary Leiomyosarcomamentioning

confidence: 99%

“…components, whereas sarcoma (LMS and RMS) are more likelytospreadhaematogenously [37,38,40,52].Thecarcinomatous component may be identified at pelvic and pleural sites.Finally,theleadingcauseofdeathisduetotheremarkable progression of the disease. Large multicystic masses often extend from the pelvic floor with omental, peritoneal, and thoracic metastasis along with complex collection of serosanguinousascites.…”

Section: Primary Leiomyosarcomamentioning

confidence: 99%

“…Although the number of cases of fallopian tube LMS is too smalltoshowstatisticallysignificantcorrelations,potentially important prognostic factors include age, grade, depth of tumourinvasion,extentofdisease,amountofresidualtumour after primary surgery, tumour size, and number of mitoses [12,26,28,41,[51][52][53].…”

Section: Primary Leiomyosarcomamentioning

confidence: 99%

See 2 more Smart Citations

Sarcomas of the Fallopian Tube: Disentangling a Rare Entity

Zagouri

Dimopoulos²,

Thomakos³

et al. 2011

Onkologie

View full text Add to dashboard Cite

Sarcomas of the fallopian tube are exceedingly rare malignancies. They have been considered the most lethal of all gynaecological malignancies with high metastatic potential, frequent recurrences and cancer-related deaths. The reported pathological types of the fallopian tube sarcomas are malignant mixed mullerian (mesodermal) tumours or carcinosarcomas, leiomyosarcomas, rhabdomyosarcomas, liposarcomas, and synovial sarcomas. The rarity of these sarcomas and their often aggressive clinical course has resulted in a relatively limited amount of literature. Thus a single hospital or specialist cannot gain sufficient experience with these tumours. This review article tries to elucidate this uncommon malignancy, in a systematic way, focusing on the different pathological types, epidemiology, risk factors, diagnosis, survival, and different therapeutic modalities (surgery, chemotherapy, and radiotherapy).

show abstract