Sarcoidosis With Retinal Involvement

Goldberg, Sol; Newell, Frank W.

doi:10.1001/archopht.1944.00890080021002

Cited by 23 publications

(5 citation statements)

References 2 publications

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“…Oedema of the macula has also been observed in active sarcoid retinopathy (Goldberg and Newell, 1944;Chumbley and Kearns, 1972, one case out of four; Letocha et al, 1975;Turner et al, 1975;Karma 1979, three of 21 cases with fundal changes). Fine and Flocks (1953) and Hart and Burde (1979) observed contluent swelling of the optic disc and of the macula.…”

Section: The Ocular Fundusmentioning

confidence: 95%

“…Perivascular infiltration may result in narrowing of the lumen, and the vessel wall itself may be involved (Levitt, 1941;Gass and Olson, 1973). Rarely, venous thrombosis has been reported (Goldberg and Newell, 1944). Like other forms of periphlebitis, that of sarcoidosis may be complicated by haemorrhage.…”

Section: The Ocular Fundusmentioning

confidence: 99%

“…In view of the frequency of concurrent involvement of the fundus oculi and the central nervous system, noted below, differential diagnosis frorn papilloedema due to intracranial sarcoidosis or to involvement of the optic nerve within the optic foramen, discussed in Chapter 14, p. 305, may be difficult (james et al, 1967). Nodular masses, presumably of sarcoid granuloma, may be seen at the margin of or over the optic nerve head (Goldberg and Newell, 1944;Mackensen, 1952;Laties and Scheie, 1972) . They follow an unpredictable course; Laties and Scheie watched the shrinkage of two such lesions in a patient with BHL and lung changes, leaving very minor 'gliosis' and no visual defect; in Case 1 of Goldberg and Newell (1944), a white mass extending three dioptres into the vitreous and associated with haemorrhage led to extensive new vessel formation.…”

Section: The Ocular Fundusmentioning

confidence: 99%

“…Nodular masses, presumably of sarcoid granuloma, may be seen at the margin of or over the optic nerve head (Goldberg and Newell, 1944;Mackensen, 1952;Laties and Scheie, 1972) . They follow an unpredictable course; Laties and Scheie watched the shrinkage of two such lesions in a patient with BHL and lung changes, leaving very minor 'gliosis' and no visual defect; in Case 1 of Goldberg and Newell (1944), a white mass extending three dioptres into the vitreous and associated with haemorrhage led to extensive new vessel formation. In other cases, masses at the optic nerve head have been part of more widespread ocular changes, with an unfavourable course which has resulted in a few in indications for enucleation, providing the possibility of histology which confirmed the granulomatous nature of the nodular masses (Laval, 1952;Kelley and Green, 1973).…”

Section: The Ocular Fundusmentioning

confidence: 99%

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Sarcoidosis

Scadding

Mitchell

1985

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Section: The Ocular Fundusmentioning

confidence: 95%

Section: The Ocular Fundusmentioning

confidence: 99%

Section: The Ocular Fundusmentioning

confidence: 99%

Section: The Ocular Fundusmentioning

confidence: 99%

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Sarcoidosis

Scadding

Mitchell

1985

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“…Goldberg and Newell reported 2 cases with single lesions of the fundus but primarily involving retinal infiltration with accompanying retinal vascular changes. 15 They speculated that perhaps in those cases of retinal infiltration with sarcoid the retinal vascular changes might precede the appearance of the visible fundus mass, as was directly observed in one of their cases.…”

Section: Discussionmentioning

confidence: 85%

Solitary choroidal mass as the presenting sign in systemic sarcoidosis.

Olk¹,

Lipmann²,

Cundiff³

et al. 1983

British Journal of Ophthalmology

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SUMMARY A solitary choroidal mass with an overlying neurosensory retinal detachment was seen in an otherwise healthy 25-year-old Caucasian female. Ocular and general physical examinations, serum chemistry, and pathological examination of a lymph node biopsy confirmed sarcoidosis as the cause for the choroidal mass. Treatment with systemic steroids resulted in resolution of the lesion and return of normal visual acuity. Case reportA 25-year-old Caucasian female was seen by her local ophthalmologist and referred for retinal examination because of central blurring in her left eye for the previous 3 days. The patient noticed no redness, pain, or photophobia. Ocular history revealed one sister who was noted to have a unilateral eye defect which by history was suggestive of a coloboma. The sister was not examined. Past medical history was negative except for an upper respiratory infection one month prior to ocular examination. Four months previously the patient had given birth to a full-term, healthy child, delivered by caesarean section because of prolonged labour. After delivery the patient had a raised white blood count, the cause of which was never determined. There was no history of fever, weight loss, or anorexia. The patient abused neither drugs nor alcohol.Ocular examination revealed best corrected visual acuity of 20/20 OD, 20/100 OS. Applanation intraocular tensions were 12/13. External examination was normal. The pupils were 4 mm, equal, round, and reacted to light directly and consensually without an afferent defect. A muscle balance test showed orthophoria. Motility tests revealed full ductions and versions. A photo stress test showed a delay on the left greater than one minute compared with the right. American Optical colour plates showed 12 of 15 correct OD, 0 of 15 OS. An Amsler grid test showed a central scotoma OS. Slit-lamp examination of the anterior segment was unremarkable in both eyes.

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Sarcoidosis

Ferguson¹,

Paris²

1958

AMA Arch Intern Med

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Sarcoidosis With Retinal Involvement

Cited by 23 publications

References 2 publications

Sarcoidosis

Sarcoidosis

Solitary choroidal mass as the presenting sign in systemic sarcoidosis.

Sarcoidosis

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