Sarcoidosis With Involvement of the Appendix

Clarke, H

doi:10.1001/archinte.1983.00350080125027

Cited by 15 publications

(4 citation statements)

References 4 publications

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“…Of these, three patients had a normal-looking appendix without evidence of inflammation 3 4 7. The other four had inflamed appendices with appendicitis confirmed on histology, of which three perforated 2 5 6 8…”

Section: Discussionmentioning

confidence: 99%

Appendicular sarcoidosis mimicking acute appendicitis

et al. 2012

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Appendicular sarcoidosis is a very rare cause of acute abdominal pain, with only seven cases reported previously in the literature. A 45-year-old woman, known to have sarcoidosis, presented to the emergency department with a 1-week history of epigastric and right iliac fossa abdominal pain. At diagnostic laparoscopy, an acutely inflamed appendix was found and removed as well as an omental mass which was biopsied. Subsequent histopathological examination of the appendix demonstrated appendicular sarcoidosis without acute appendicitis and chronic inflammatory changes in the omental biopsy. The patients' symptoms completely resolved postoperatively. It is important to undertake urgent operative intervention in patients with sarcoidosis who present with right iliac fossa pain, owing to the high risk of perforation.

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Section: Discussionmentioning

confidence: 99%

Appendicular sarcoidosis mimicking acute appendicitis

et al. 2012

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“…Sarcoidosis may rarely involve the appendix. 138,139 Occasionally this will result in appendiceal perforation. 139…”

Section: Appendixmentioning

confidence: 99%

Hepatic, Splenic, and Gastrointestinal Involvement with Sarcoidosis

Judson

2002

Seminars in Respiratory and Critical Care Medicine

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Sarcoidosis is a multisystem granulomatous disease of unknown cause that primarily affects the lung and lymphatic systems of the body. However, any organ may be affected, including the abdominal organs and gastrointestinal tract. As with other forms of sarcoidosis, abdominal sarcoidosis presents diagnostic, prognostic, and therapeutic dilemmas. This article reviews the various forms of abdominal sarcoidosis, with particular attention given to methods of diagnosis and treatment options.

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“…It is often difficult to differentiate between the two, sarcoidosis and Crohn's disease; however, the presence of plasma cell infiltrate favors the latter and presence of systemic sarcoid favors the former. Clarke and colleagues 46 reported on a patient with systemic sarcoidosis who developed acute appendicitis. There was no evidence of infection, but granulomas were seen in the appendiceal wall.…”

Section: Sarcoidosis Of the Appendixmentioning

confidence: 99%

“…Munt 42 Bystrom 44 Macleod 45 Shinefeld, Rubinow 43 Clarke et al 46 were reported prior to 1986, [55][56][57][58] and Barr and colleagues reported another eight cases from a series of 680 patients with ulcerative colitis or extrapulmonary sarcoidosis. The onset of either condition bore no relationship to the activity or the extent of the other, suggesting that the two diseases were independent.…”

Section: Table 3 Case Reports Of Appendicial Sarcoidosismentioning

confidence: 99%