Sarcoidosis with Arthritis

Bianchi, F; Keech, M. K.

doi:10.1136/ard.23.6.463

Cited by 21 publications

(8 citation statements)

References 32 publications

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“…In three with long-standing arthritis they found a characteristic picture of typical granulomata in the synovium accompanied by a diffuse non-specific inflammatory component, consisting of infiltration of leucocytes and plasma cells, and proliferation of fibroblasts. Similar granulomatous changes were found by Bianchi and Keech (1964) in five of six patients biopsied, when they investigated twelve patients with joint disease presenting in an arthritis clinic, all of whom were shown to have sarcoidosis.…”

Section: Discussionsupporting

confidence: 64%

“…In two patients erosions appeared to have extended from the bone into the joint space. A similar process had occurred in one of the five cases of Sokoloff and Bunim (1959), and joint-space narrowing with sclerosis was demonstrated in one patient described by Bianchi and Keech (1964). Bony lesions of the phalanges are less common than earlier reports suggested, L6fgren (1953) finding them present in only three of 212 patients and Mather (1957) in nine of 120.…”

Section: Discussionsupporting

confidence: 58%

“…Sokoloff and Bunim (1959) investigated five cases of sarcoidosis with arthritis, and found granulomata in the synovium of affected joints in three of the five. Williams (1961) described seven patients presenting with arthritis, in whom systemic manifestations and erythema nodosum were common, and Bianchi and Keech (1964) discussed the features of twelve cases of sarcoidosis presenting in a rheumatology clinic.…”

mentioning

confidence: 99%

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The joint disease of sarcoidosis.

Gumpel¹,

Johns²,

Shulman³

1967

Annals of the Rheumatic Diseases

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Section: Discussionsupporting

confidence: 64%

Section: Discussionsupporting

confidence: 58%

mentioning

confidence: 99%

See 1 more Smart Citation

The joint disease of sarcoidosis.

Gumpel¹,

Johns²,

Shulman³

1967

Annals of the Rheumatic Diseases

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“…As in other descriptions of the syndrome (9,14,15, IS), early cases with fever, bilateral hilar lymphadenopathy, erythema nodosum, and peripheral lymphadenopathy were predominant. Biopsy showed noncaseating granuloma in the synovium of half of Bianchi and Keech's cases (14) and in Myers' cases (15). Osseous lesions were remarkably absent (15,16) or rare (1 3,14).…”

Section: Discussionmentioning

confidence: 99%

Extensive phalangeal cystic lesions

Schriber

Firooznia

1975

Arthritis & Rheumatism

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A young black man is presented with a 33-month course of insidious but eventually striking hand deformity and limitation of motion in the absence of any other symptoms. Radiologic and histologic findings of the digits support the diagnosis of sarcoidosis, though physical, laboratory, and chest x-ray examination show no evidence of this multisystem disease.Osseous involvement is a well-recognized feature of sarcoidosis, occurring rarely in the absence of skin lesions or chronic, multiorgan system involvement. When present it is usually not symptomatic. A patient was presented with complaints limited to the hands and feet throughout a 33-month course. The possibility is raised that, in rare instances, sarcoid may be limited to the skeletal system. The patient was well until January 1971 when he noted swelling and mild discomfort in the area of the second left metacarpophalangeal joint, which lasted several days and resolved. This condition recurred soon afterward in several areas of both hands. At all times, swelling was the predominant feature, although there was mild discomfort at times, especially in the morning. He came to the outpatient department at Bellevue Hospital in early 1971 for this complaint. Radiographic examination of the hands showed several cystic bony lesions, but the patient did not return for further workup or treatment. CASE REPORTDuring the next 19 months he noted persistent swelling of the fingers with occasional mild discomfort and morning stiffness. However, he was not greatly bothered and continued his activities as a student, even playing basketball occasionally. He sought no medical attention during this time. I n the summer of 1972, the patient noted that the swelling increased and that he now had difficulty performing certain fine movements because of relatively painless limited motion. When school started in September 1972, he noted he could not hold a pencil properly and sought medical attention for the second time at Bellevue Hospital. Pain was never a major feature and there were no acute at tacks.There was no history of fever, malaise, rash, other musculoskeletal complaints, visual disturbances, cough, or shortness of breath. Past medical history and family history were noncontributory. On admission to Bellevue Hospital in September 1972, physical examination revealed a wellnourished, well-developed black man who appeared healthy, except for obviously swollen, sausage-like fingers. Vital signs, head, eyes, ears, nose, and throat were normal. There were no skin lesions. There were several y2 X v2 cm soft, movable, nontender nodes in both axillae. The chest cage, heart, and lungs were normal. The abdomen showed no organo-

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“…Histologisch finden sich sowohl bei der akuten wie bei der chronischen Sarcoid-Arthritis in typischen Fällen die charakteristischen Granulome in der Synovialis wie auch-in den Sehnenscheiden (8,11,12,13,19,22,57,79,81). Speziell bei der akuten Sarcoid-Arthritis findet man häufig auch unspezifische Reaktionen mit mäßiger Proliferation der synovialen Deckzellen und geringfügigen Rundzellinfiltrationen ohne Granulome (8,14,19,23,79,81,87 ...hlrd~1 "hn ",,,I, un).…”

Section: Rheumatic Syndromes In Sarcoidosisunclassified

Rheumatische Syndrome bei der Sarcoidose

Müller¹,

Wurm²

1980

Akt Rheumatol

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Sarcoidosis with Arthritis

Cited by 21 publications

References 32 publications

The joint disease of sarcoidosis.

The joint disease of sarcoidosis.

Extensive phalangeal cystic lesions

Rheumatische Syndrome bei der Sarcoidose

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