Sarcoidosis: Pulmonary and Skin Studies Before and After ACTH and Cortisone Therapy

Salomón, Ana Lúcia Ribeiro; Appel, B.; Collins, Sharon L.; Herschfus, J.A.; Segal, Maurice S.

doi:10.1378/chest.29.3.277

Cited by 18 publications

(12 citation statements)

References 7 publications

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“…Evidence of mild airways obstruction in four patients suggested the possibility of bronchial involvement. The presence of an increased residual volume and functional D, tesidual capacity in two patients in the absence of airways obstruction supports similar observations by Salomon, Appel, Dougherty, Herschfus, and Segal (1955), although their findings were attributed to bronchial obstruction. The presence of ventilated cystic spaces in the absence of airways obstruction could explain these results but bronchographic (Hayman and Hunt, 1952) and pathological (Church and Ellis, 1950) evidence suggests that the cysts do not communicate directly with the bronchial tree.…”

Section: Discussionsupporting

confidence: 89%

Pulmonary Function in Scleroderma

Ritchie¹

1964

Thorax

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Section: Discussionsupporting

confidence: 89%

Pulmonary Function in Scleroderma

Ritchie¹

1964

Thorax

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“…Restriction of lung volumes, airways obstruction, and a mixed pattern combining features of with pulmonary involvement (Baldwin et al, 1949;Spain and Thomas, 1950;Salomon et al, 1955). It has been suggested that airways obstruction is a relatively late manifestation of the disease and that the earliest functional abnormality is impairment of the transfer factor (Catterall and Rowell, 1963;Hughes and Lee, 1963;Wilson et a!, 1964).…”

Section: Discussionmentioning

confidence: 99%

Serial pulmonary function tests in progressive systemic sclerosis.

Bagg¹,

Hughes²

1979

Thorax

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Serial pulmonary function tests were performed on nine patients with progressive systemic sclerosis over a mean period of ten years. Abnormality was seen to develop both early and late in the course of the disease, and the earliest abnormality observed was impairment of the transfer factor. Deterioration of some aspect of pulmonary function was noted in each case, evidence of restriction or air trapping being seen with equal frequency. Two patients died, both of causes unrelated to their pulmonary involvement, and even pronounced early involvement of the lungs did not necessarily imply a bad prognosis.

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“…Impaired diffusion has been suggested as the earliest pulmonary function alteration in scleroderma (5,8). Obstructive lung disease has been noted alone or in conjunction with restrictive lung disease (2,4,5,7,9,11), but has been considered a relatively late manifestation of disease (2.8).…”

mentioning

confidence: 99%

Pulmonary Function in Scleroderma

Guttadauria

Ellman

Emmanuel

et al. 1977

Arthritis & Rheumatism

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Pulmonary function tests were performed in 45 patients with scleroderma. Thirteen patients (29%) were found to have restrictive disease, 12 patients (27%) were found to have obstructive disease, and 19 patients (42%) had small airway disease (SAD). Smoking did not seem to be a factor underlying either obstructive or small airway disease in these patients. A low diffusing capacity was most common in patients with restrictive disease and rarely the only abnormality in pulmonary function. S A D was usually found in patients who had normal chest radiographs and no pulmonary symptoms and was often the only abnormality. S A D is therefore an early and sensitive indicator of pulmonary involvement in scleroderma.Since the report by Baldwin et a1 in 1949 (I), restriction of lung volumes and impaired diffusion have been considered the characteristic pulmonary function abnormalities in patients with the pulmonary involvement of scleroderma. Studies since then (2-1 1)

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Sarcoidosis: Pulmonary and Skin Studies Before and After ACTH and Cortisone Therapy

Cited by 18 publications

References 7 publications

Pulmonary Function in Scleroderma

Pulmonary Function in Scleroderma

Serial pulmonary function tests in progressive systemic sclerosis.

Pulmonary Function in Scleroderma

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