Sarcoidosis presenting with Polyarthritis

The joint disease of sarcoidosis.

“…Unless a chest x ray showing hilar adenopathy was obtained, the diagnosis was easily missed. A marked degree of systemic disturbance with fever and a rapid erythrocyte sedimentation rate is common, and was noted as a special feature by Williams (1961) in a description of seven patients admitted to hospital with a polyarthritis, later diagnosed as sarcoidosis.…”

“…Sokoloff and Bunim (1959) investigated five cases of sarcoidosis with arthritis, and found granulomata in the synovium of affected joints in three of the five. Williams (1961) described seven patients presenting with arthritis, in whom systemic manifestations and erythema nodosum were common, and Bianchi and Keech (1964) discussed the features of twelve cases of sarcoidosis presenting in a rheumatology clinic.…”

The Association of Sarcoidosis, Erythema Nodosum, and Arthritis

“…Case 3.-A 42-year-old white female machine op¬ erator was admitted to the University of Virginia Hospital on Aug 6,1965. The patient reported a his¬ tory of recurrent pharyngitis during the spring and, in May 1965, developed tender swelling of the knees associated with periarticular cutaneous nodules.…”

“…Although erythema nodosum may contribute significantly to the signs and symptoms of the syndrome, it is probably a good prog¬ nostic sign.4'5 Articular symptoms have been less frequently reported but have been em¬ phasized by both Williams 6 …”