Sarcoidosis presenting in tattoos

Cutaneous sarcoidosis: clinicopathologic study of 76 patients from Lebanon

“…4 The frequencies of the occurrence of polarizable foreign material in sarcoidosis in the various studies reported, which were essentially conducted in North American and European populations, were in the range of 13-50%. [31][32][33][34][35] A novel interesting histopathologic feature observed in our study concerned the presence in 5% of cases of a grenz zone, which is defined as a narrow area of the papillary dermis uninvolved by underlying pathology. In addition, all of these cases had systemic sarcoidosis.…”

“…In fact, this observation may support the hypothesis that particulate foreign material may serve as a nidus for granuloma formation in sarcoidosis. [31][32][33][34][35] A novel interesting histopathologic feature observed in our study concerned the presence in 5% of cases of a grenz zone, which is defined as a narrow area of the papillary dermis uninvolved by underlying pathology. 36 Historically thought to be an exclusive feature of granuloma faciale, this feature has also been demonstrated in other cutaneous inflammatory conditions, and neoplastic benign and malignant tumors, as well as infectious entities.…”

Localization of cutaneous sarcoidosis: From trauma to scars

“…It has been suggested that the presence of foreign bodies or other exogenous antigens introduced into the dermis by an old injury might provide the stimulus necessary for granuloma formation when a genetically predisposed subject develops sarcoidosis. [1][2][3][4] We have also demonstrated the presence of foreign bodies in all of our 4 patients with scar sarcoidosis located in the knees. We consider that the foreign bodies and other antigens present in these scars may be the cause of scar sarcoidosis.…”

Clinical and histopathological analysis of specific lesions of cutaneous sarcoidosis in Korean patients

“…Cutaneous sarcoidosis has also been known to be observed at sites of chronic trauma (11)(12)(13)(14). Inactive scars that have been quiescent for years become sarcoidal lesions with a red or purple hue and indurations (2).…”