Sarcoidosis of the upper respiratory tract

Page, J. R.; Seth, Soutrik

doi:10.1017/s0022215100071255

Cited by 10 publications

(5 citation statements)

References 12 publications

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“…Although paranasal sarcoidosis has been shown to resolve in rare cases, 9 severe disease may not resolve, despite intensive medical therapy. 7 ,8 One of eight patients in a recent series (12.5%) 1 1 and four of 28 in a larger series (14%) 8 failed medical treatment.…”

Section: Discussionmentioning

confidence: 99%

The Role of Endoscopic Sinus Surgery in Chronic Sinonasal Sarcoidosis

Kay

Har‐El

2001

American Journal of Rhinology

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The aim of this study was to define a role for endoscopic sinus surgery (ESS) in the treatment of chronic sinonasal sarcoidosis. All patients seen for sinonasal sarcoidosis in an otolaryngology practice in a tertiary care center from 1991 to 2000 were reviewed. Of 86 patients, 6 were treated with ESS for an operative rate of 7%. Surgeries were performed on those patients with significant sinonasal anatomic blockage. This included nasal obstruction from nasal polyposis and chronic and recurrent acute sinusitis from granulomatous lesions of the ostiomeatal complex. Patients remained symptom free for years after surgery on a nasal steroid regimen. Endoscopic sinus surgery is a viable treatment for those few patients with nasal obstruction or chronic sinusitis due to anatomic blockage from sinonasal sarcoidosis. Although it does not eradicate the disease or prevent recurrence, it does markedly improve quality of life by relieving severe symptoms and reducing the need for systemic steroids. This is the first study to advocate a role for surgery in sinonasal sarcoidosis beyond biopsy and management of complications. Although it may not be the appropriate approach for every patient, ESS certainly should be considered in the treatment options.

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Section: Discussionmentioning

confidence: 99%

The Role of Endoscopic Sinus Surgery in Chronic Sinonasal Sarcoidosis

Kay

Har‐El

2001

American Journal of Rhinology

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“…If the symptoms are confined to the nasal mucosa, topical preparations of corticosteroids have much to offer. There have been reports of spontaneous regression of nasal sarcoidosis (Page and Seth, 1969). Surgery, apart from obtaining biopsy tissues, has not been found to be helpful.…”

Section: Discussionmentioning

confidence: 99%

Ethmoidal sarcoidosis

1994

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“…Raised serum angiotensin converting enzyme levels (ACE) are detected in most and 15 per cent of patients have abnormal liver function. 1 The Kveim and Mantoux tests were used but are no longer available because of the potential for prion contamination and HIV infection. Tissue diagnosis is now the gold standard and biopsy of minor salivary glands can achieve this in 58 per cent of cases.…”

Section: Introductionmentioning

confidence: 99%

“…The otorhinolaryngological manifestations of sarcoidosis are summarized in Table II. [1][2][3] Case report A 55-year-old Caucasian man was referred to the ENT department with a right-sided hearing loss and tinnitus of approximately one-year's duration. There were no (Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Mesotympanic sarcoidosis

Banerjee

Gleeson

2005

J. Laryngol. Otol.

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Sarcoidosis often presents with signs and symptoms within the head and neck. In this region, it most commonly affects the nose, larynx, parotid and cervical lymph nodes. Within the ear, it usually causes sensorineural hearing loss of varying severity. We report a patient in whom sarcoidosis involved the middle ear and presented with a conductive hearing loss. Granulomata were found in the middle ear during an exploratory tympanotomy. The granulomatous process had caused necrosis of the long process of incus and was also encasing the chorda tympani nerve. Histological examination confirmed the diagnosis.

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Sarcoidosis of the upper respiratory tract

Cited by 10 publications

References 12 publications

The Role of Endoscopic Sinus Surgery in Chronic Sinonasal Sarcoidosis

The Role of Endoscopic Sinus Surgery in Chronic Sinonasal Sarcoidosis

Ethmoidal sarcoidosis

Mesotympanic sarcoidosis

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