Sarcoidosis Involving the Lacrimal Gland

Coexistence of Sjögren's syndrome and sarcoidosis: a report of five cases

“…Sicca symptoms are typical of SS; however, sarcoidosis may affect the exocrine glands producing sicca symptoms that are difficult to distinguish from those caused by SS (18). Cases where the sicca symptoms are the only presenting features in sarcoidosis are rare but they have been increasingly reported (13–15, 19, 20). Ocular involvement was reported in 25% of patients with sarcoidosis, anterior uveitis being the most common feature.…”

“…Ocular involvement was reported in 25% of patients with sarcoidosis, anterior uveitis being the most common feature. Although involvement of the lacrimal gland was reported in 3% of the cases, gallium uptake was noted in about 80% of the time with keratoconjunctivitis sicca manifesting in about 16% of the cases (19). The salivary glands could be affected by sarcoidosis as well and was reported in 6% of the cases.…”

“…Other potentially shared features are the involvement of the joints and skin (13, 24). Ankle swelling, for example, might be caused by arthritis of the ankle joints associated with either condition (19, 24). Although the two diseases share many similarities, indicating a common or a similar pathophysiological mechanism, they show a different serologic profile.…”