Sarcoidosis (Boeck), Lymphogranulomatosis Benigna (Schaumann); Observations on the Bone Marrow obtained by Sternal Puncture

Misnomers are terms for any of medical conditions whose name does not reflect the pathophysiological reality. In the field of dermatology, it is interesting to note that there are some misnomers about lupus. Lupus is Latin for wolf, and it comes from the facial appearance that was thought to resemble the bites of a wolf. Until the 19th century, lupus was most commonly caused by cutaneous tuberculosis (TB), so some of the misnomer related to TB. Other misnomers encountered in lupus have arisen from the lack of understanding of the underlying etiology, pathogenesis and histopathological features, due to imprecise translations.

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“…Benign miliary lupoid is a misnomer since the condition is a type of cutaneous sarcoidosis and lupus does not have a role in the disease. 12…”

Section: Benign Miliary Lupoid Of Boeckmentioning

confidence: 99%

Lupus and lupoid misnomer: issues and challenges

Pourazizi

Kabiri

Saffaei

et al. 2016

Lupus

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Sarcoidosis

McCort¹,

Wood²,

Hamilton³

et al. 1947

Arch Intern Med (Chic)

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Sarcoid Diagnosed by Needle Biopsy of the Spleen

Block¹

1952

JAMA

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ceded by carcinoma in situ. If this be true, then a cervical biopsy obtained one or even more years previous to the time the clinical signs and symptoms of cervical cancer appear may reveal this histological picture of surface carcinoma, and the routine examination of the asympto¬ matic cervix by biopsy as done in many detection clinics becomes not only a useful but an almost imperative pro¬ cedure.Reexamination of the tissue from the eight cases in which a previous uterine curettage had been performed disclosed previously unrecognized carcinoma in situ in only two cases (table 3). It must be remembered, how¬ ever, that unless the cervical canal is purposely curetted, cervical tissue is obtained by uterine curettage only by accident. Actually, in the eight curettage specimens, cer¬ vical tissue was obtained in only four of them, two of which showed carcinoma in situ while the other two had no evidence of abnormality. This should reemphasize the advantage of curetting the cervical canal as well as biopsying the cervix when the uterus is being curetted. SUMMARY AND CONCLUSIONSIn summary, 13 cases of carcinoma in situ not treated as such were studied. The ultimate clinical course was known in all cases. Three of the lesions remained in the noninvasive stage after 2, 4, and 6 years, respectively, while the remaining 10 had progressed to various clinical stages of cervical cancer 1 to 17 years later. How long intraepithelial carcinoma was present before the original biopsy was obtained is, of course, a matter of conjecture.Consideration of these clinical and histological data seems to admit the following conclusions: 1. Carcinoma in situ is potentially invasive, and, if untreated, may progress to clinically evident cervical cancer. 2. As this study is retrospective, it does not indicate that carcinoma in situ always becomes invasive. It does, however, indi¬ cate that clinical cervical cancer is preceded by carci¬ noma in situ in too large a proportion of cases to be coincidental. 3. The clinical course of cervical cancer rep¬ resents only a small segment of its life history and the greater part of its existence is spent in the preinvasive stage. 4. If the patient who is destined to have cervical cancer is fortunate enough to have a cervical biopsy within five years previous to the time she would have de¬ veloped clinical signs and symptoms of cervical cancer, the biopsy specimen is likely to show carcinoma in situ. If the lesion is diagnosed and treated in that stage, the patient's chances of being cured are almost 100%.Sarcoid is a generalized disease with fairly characteristic but nonspecific, noncaseating granulomas found most frequently in the hematopoietic tissues. Clinically it is usually manifested by a chronic course with fever and various combinations of lymphadenopathy, splenomegaly, and hepatomegaly. Leukopenia and reversal of the protein albumin-globulin ratio are frequent.A fairly characteristic diffuse lesion in the lung fields, hilar lymphadenopathy, and, less frequently, osteolytic lesions of the small...

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Sarcoidosis (Boeck), Lymphogranulomatosis Benigna (Schaumann); Observations on the Bone Marrow obtained by Sternal Puncture

Abstract: The appelation marcoido is a generic term meaning ))resembling flesh)). It is used to signify a type of reaction in the skin. It does not necessarily imply a specific etiology.

Cited by 10 publications

References 14 publications

Lupus and lupoid misnomer: issues and challenges

Lupus and lupoid misnomer: issues and challenges

Sarcoidosis

Sarcoid Diagnosed by Needle Biopsy of the Spleen

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