Sarcoidosis Associated with Connective Tissue Diseases: Report of 3 Cases.

Ishioka, Shinichi; Yamanishi, Yuji; Hiyama, Keiko; Maeda, Akihiro; Maeda, Hitoshi; Yamakido, Michio

doi:10.2169/internalmedicine.38.984

Cited by 1 publication

(1 citation statement)

References 14 publications

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“…31 A prospective study found only 4% of sarcoidosis patients developed CTD after 10 years. 32 However, only 1% of CTD patients followed up for 10 years were subsequently diagnosed with sarcoidosis, which seems to imply that sarcoidosis patients may be more likely to have features of CTD, but CTD patients may not be more likely to develop sarcoidosis. 33…”

Section: Connective Tissue Diseasementioning

confidence: 95%

Overlap Syndromes in Sarcoidosis: Clinical Features and Outcomes

James

2020

Semin Respir Crit Care Med

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Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomatous inflammation. While pulmonary sarcoidosis is most common, extrapulmonary involvement occurs in 50 to 74% of patients and can be the presenting abnormality in some patients. The diagnosis of sarcoidosis is based on a compatible clinical presentation in combination with granulomas on histology and exclusion of other causes. However, the absence of a diagnostic biomarker for sarcoidosis, in addition to the overlap of granulomatous inflammation and nonspecific clinical findings with other diseases, often results in a delayed diagnosis. Sarcoidosis overlap syndromes are typically described when sarcoidosis is diagnosed in the presence of another disease (concurrently or sequentially) with shared clinical and histologic features, or when sarcoidosis presents with clinical features typically observed in, but not diagnostic of, other diseases. Awareness of overlap syndromes is important for clinicians to avoid diagnostic errors and evaluate for concomitant diagnoses that may impact the management and outcome of sarcoidosis. This article is intended to provide an overview of these presentations and the most commonly associated diseases, with attention to their prevalence, clinical features, and reciprocal impacts on disease outcomes.

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Section: Connective Tissue Diseasementioning

confidence: 95%

Overlap Syndromes in Sarcoidosis: Clinical Features and Outcomes

James

2020

Semin Respir Crit Care Med

View full text Add to dashboard Cite

show abstract

Sarcoidosis Associated with Connective Tissue Diseases: Report of 3 Cases.

Cited by 1 publication

References 14 publications

Overlap Syndromes in Sarcoidosis: Clinical Features and Outcomes

Overlap Syndromes in Sarcoidosis: Clinical Features and Outcomes

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