Sarcoidosis and Its Ophthalmic Manifestations

Sarcoidosis presenting as orbital pseudotumor

“…Ocular involvement has been reported in 25-60% of the patients (7). Seven percent of the patients with sarcoidosis may fi rst see an ophthalmologist with complaints of ocular involvement (8). Anterior uveitis is the most common ocular manifestation, followed by posterior uveitis which may have severe impacts on visual acuity (9).…”

Usefulness of quantifying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis

“…Other possible sources of KL-6 in the inflamed eyes may be corneal and conjunctival cells. Though their contribution rates to raise systemic level of KL-6 might be small, sarcoid granulomas are seen in 7% to 17% of sarcoidosis patients with ocular involvement [13,14,28], suggesting that sarcoidosis frequently invades into ocular surface. Thus, it is possible that inflamed eye with sarcoidosis is one of the possible candidate organs to raise KL-6 level.…”

Bilateral Acute Retinopathy with Vitreous Hemorrhage as a First Manifestation of Sarcoidosis: Case Report

“…10 Posterior segment lesions are reported in about 14-28% of patients with ocular sarcoidosis and include vitreitis, chorioretinitis, periphlebitis, vascular occlusion, retinal neovascularization, and optic nerve head granuloma. 11,12 Sarcoidosis optic neuropathy is rare but can cause permanent blindness. 6 Peripheral retinal neovascularization is generally seen in patients with a defined vasoocclusive disorder, such as a branch retinal vein occlusion, and may even simulate a sea fan, similar to that seen in sicklecell disease.…”