Sarcoid Variant of Actinic Granuloma: Is It Annular Sarcoidosis?

Gambichler, Thilo; Herde, M.; Hoffmann, K.; Stücker, M.; Altmeyer, Peter; Jansen, Thomas

doi:10.1159/000051792

Cited by 6 publications

(2 citation statements)

References 10 publications

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“…12,46 A case of AG associated with erythema nodosum also supports the theory that both conditions belong to the same spectrum of noninfectious granulomatosis. 57 Our group reported a case of EAGCG on photoexposed areas in a patient affected by X-linked dominant protoporphyria.…”

Section: Systemic Associationsmentioning

confidence: 64%

Elastolytic Actinic Giant Cell Granuloma

Gutiérrez‐González

Pereiro

Toribio

2015

Dermatologic Clinics

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Section: Systemic Associationsmentioning

confidence: 64%

Elastolytic Actinic Giant Cell Granuloma

Gutiérrez‐González

Pereiro

Toribio

2015

Dermatologic Clinics

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“…For example, a clinical presentation similar to AEG has been described in patients with systemic sarcoidosis. Such patients are probably best classified as having an annular variant of cutaneous sarcoidosis . However, lesions that are clinically and histopathologically compatible with AEG, without a sarcoidal pattern of inflammation, have been described in patients with systemic sarcoidosis .…”

mentioning

confidence: 99%

The sarcoidal variant of annular elastolytic granuloma

et al. 2013

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A 59-year-old woman who was otherwise healthy presented for evaluation of an annular plaque on the left forehead. The plaque had an erythematous scaly raised border, and the central portion was hypopigmented and subtly atrophic (Figures 1 and 3). The plaque was solitary, as a full body examination did not reveal additional cutaneous lesions. It was asymptomatic and longstanding but had been slowly expanding. A biopsy of the plaque had been previously performed in 2004, at which time the patient was under the care of a different clinical team. At the time, scant clinical information was included with the specimen. The 2004 biopsy showed tightly packed nodular collections of histiocytes and was interpreted as probably representing sarcoidosis. Subsequent systemic evaluation for sarcoidosis, including a chest x-ray and an angiotensin converting enzyme (ACE) level, was negative.The patient recently presented to our institution, where our clinicians were unable to reconcile the histopathology with the clinical presentation. Therefore, an additional biopsy was performed. The biopsy showed dense small and large compact sarcoidal aggregations of histiocytes distributed in a vaguely band-like configuration in the upper dermis (Figures 2 and 4). The aggregations were accompanied by small lymphocytes (Figures 4 and 5). A diagnosis of sarcoidal granulomatous dermatitis was rendered, and a differential diagnosis that included sarcoidosis, infection, granulomatous rosacea, and a cutaneous manifestation of Crohn's disease was offered. Special stains (Fite, PAS-D, and Brown-Brenn) were performed and failed to reveal organisms (mycobacteria, fungi and bacteria, Fig. 1. Frontal view displaying an annular plaque with an erythematous raised border and central subtle atrophy with hypopigmentation.

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Actinic Granuloma

2017

Diagnostic Pathology: Nonneoplastic Dermatopathology

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Sarcoid Variant of Actinic Granuloma: Is It Annular Sarcoidosis?

Cited by 6 publications

References 10 publications

Elastolytic Actinic Giant Cell Granuloma

Elastolytic Actinic Giant Cell Granuloma

The sarcoidal variant of annular elastolytic granuloma

Actinic Granuloma

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