Sarcoid uveitis: A case report and systematic review of literature

Shen, Junhui; Su, Zhipeng; Feng, Lei

doi:10.1016/j.aopr.2022.100047

Cited by 1 publication

(1 citation statement)

References 25 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This condition involves inflammation of the uvea tract, encompassing the iris, ciliary body and choroid, as well as adjacent eye structures like the vitreous, retina, optic nerve and sclera. 1 Uveitis is classified anatomically into four types: anterior uveitis, intermediate uveitis, posterior uveitis and panuveitis. Additionally, based on aetiology, it can be categorised into three types: infectious, non-infectious and masquerade.…”

Section: Introductionmentioning

confidence: 99%

Lipid profile alterations in non-infectious uveitis: correlation with quantitative optical coherence tomography angiography parameters

Shen,

Qin,

Feng

2024

BMJ Open Ophth

Self Cite

View full text Add to dashboard Cite

Background/aimsLipid profiles have been changed in numerous chronic conditions. The impact of uveitis on lipid metabolism remains unclear.MethodsThis is a cross-sectional study included 416 patients with non-infectious uveitis (NIU) and 416 healthy subjects. Standard techniques were used to measure total cholesterol (TC), triglycerides (TG), high-density lipoprotein-cholesterol (HDLc), low-density lipoprotein-cholesterol (LDLc) levels. Quantitative optical coherence tomography angiography (OCTA) parameters were obtained from 500 eyes in each group. Correlation analysis examined the relationship between lipid profile and OCTA parameters.ResultsPatients with NIU exhibited significantly elevated TC, TG and LDLc levels compared with controls (p=0.003; p<0.001; p<0.001, respectively). Subgroup analysis revealed that HDLc was significantly lower in Behçet’s disease (p=0.024) compared with controls. Vascular density (VD) in the superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaris and optic disk were significantly decreased in NIU eyes (p<0.05, respectively) compared with controls. HDLc exhibited a significant negative correlation with VDs in the whole and parafovea SCP (r=−0.489, p=0.008; r=−0.480, p=0.0026, respectively), while LDLc showed a significant positive correlation with VDs in the whole and parafovea DCP in NIU patients (r=0.576, p=0.032; r=0.267, p=0.034, respectively).ConclusionsThe lipid profile is altered in NIU, and there are correlations between HDLc and LDLc levels and VD as measured by OCTA. Lipid profile analysis may offer valuable insights into evaluating vascular and metabolic aspects of NIU.

show abstract

Section: Introductionmentioning

confidence: 99%