Sarcoid-Like Reactions

"Resolution of the Coexisting Sarcoidosis After Treatment of Papillary Thyroid Metastases with Radioactive Iodine. A Case Report"

“…Sarcoidosis is a well-known granulomatous disorder of unknown etiology [1]. The co-existence of SA and/or sarcoid like reactions with PTC has been reported in several studies [1][2][3] which makes the diagnosis of malignant recurrence and/or its metastasis difficult without thorough investigations and multiple biopsies [4]. The defected immune system associated with SA and/or sarcoid like reactions can also be a reason for an abnormal serum thyroglobulin (Tg) result, the key marker for follow up of recurrence of differentiated thyroid cancers [5].…”

“…The coexistence of Sarcoidosis (SA) with thyroid malignancy has been reported in many cases [1][2][3]. Sarcoid-like reaction has also been seen either within the vicinity of the tumor itself or within the regional lymph nodes draining its primary tumor [4]. Abnormal immune response has been suggested for the SA and/or its reactions when it coexists with thyroid diseases [5].…”