SAPHO syndrome can cause masseter muscle involvement

Jiang, Haixu; Chen, Naigang; Li, Chen

doi:10.1111/1756-185x.14513

Cited by 3 publications

(5 citation statements)

References 2 publications

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“…However, the persistence of symptoms prompted a crucial decision to initiate intravenous infliximab infusions at a dosage of 5 mg/kg at specified intervals. 20,21 The response of the patient to infliximab in this case report was both unique and remarkable. Within the first week of infliximab treatment, the patient experienced a dramatic improvement in neck pain.…”

Section: Discussionmentioning

confidence: 74%

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Unusual cause of inflammatory backache: SAPHO syndrome

Awadh,

Gorial,

Al‐Obaidi

et al. 2023

Int J of Rheum Dis

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Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) is a rare chronic inflammatory disease that develops in adults. We present a case of SAPHO syndrome in a 37‐year‐old male presenting with gradually worsening back and neck pain for a 7‐year period. The episodes were preceded by a history of pustular skin eruptions, which first appeared on the upper trunk and then involved his face and were pustular and scarring. The purpose of presenting this case report from Iraq is to raise awareness about this rare condition, which is frequently misdiagnosed and under‐recognized.

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Section: Discussionmentioning

confidence: 74%

“…Partial relief was achieved through the administration of meloxicam, an NSAID, and sustained‐release diclofenac sodium capsules. However, the persistence of symptoms prompted a crucial decision to initiate intravenous infliximab infusions at a dosage of 5 mg/kg at specified intervals 20,21 …”

Section: Discussionmentioning

confidence: 99%

Unusual cause of inflammatory backache: SAPHO syndrome

Awadh,

Gorial,

Al‐Obaidi

et al. 2023

Int J of Rheum Dis

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“…Moreover, prevalence of muscle fatty infiltration in SAPHO patients was significantly higher than that in control individuals (30.4% vs. 2.2%, p < .01). Interestingly, a recent study also showed the masseter muscle involvement in SAPHO patients 23 …”

Section: Extracutaneous/osteoarticular Manifestationsmentioning

confidence: 94%

Extracutaneous/osteoarticular manifestations in patients with SAPHO syndrome

Hu,

Liu,

Cui

et al. 2023

Int J of Rheum Dis

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“…30 A recent study reported masseter muscle involvement in patients with SAPHO syndrome. 31 The precise mechanism underlying sarcopenia in SAPHO syndrome remains elusive. Chronic inflammation is a risk factor for sarcopenia, which may be related to the reason that elevated cytokine levels can reduce muscle mass and function.…”

Section: Sarcopeniamentioning

confidence: 99%

“…In a study encompassing 23 SAPHO syndrome patients and 46 controls, the prevalence of fatty infiltration of muscle was significantly higher in SAPHO syndrome patients than in controls 30 . A recent study reported masseter muscle involvement in patients with SAPHO syndrome 31 . The precise mechanism underlying sarcopenia in SAPHO syndrome remains elusive.…”

Section: Extra‐articular and Cutaneous Manifestationsmentioning

confidence: 99%

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome may present with extra‐articular and cutaneous manifestations

Zhang,

Zheng,

et al. 2024

Int J of Rheum Dis

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Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome may present with extra-articular and cutaneous manifestationsSAPHO syndrome is a rare autoinflammatory disease that manifests with articular and cutaneous symptoms. Although epidemiological data on SAPHO are limited, the annual incidence of the disease is estimated to be 1 in 10 000 in Caucasians and 0.00144 in 10 000 in Japanese. 1 The precise pathogenesis of SAPHO syndrome remains elusive, but it is hypothesized to have a genetic basis, linked to underlying infections and immune dysfunction.SAPHO syndrome is commonly recognized as a distinct pathological condition by researchers. However, some researchers have suggested that SAPHO syndrome can be classified as a form of spondyloarthritis, a potential transitional stage between ankylosing spondylitis (AS) and psoriatic arthritis. 2,3 Both SAPHO syndrome and spinal arthritis affect the axial and sacroiliac joints in a similar manner, exhibiting shared characteristics and even instances of co-occurrence. 4,5 SAPHO syndrome may be associated with the HLA-B27 gene. 2 Patients with AS have multisystemic damage such as the heart, lungs, kidneys, eyes, intestines, skin, and bones through the support of a large number of data. 6Common extra-articular manifestations in AS include uveitis, inflammatory bowel disease, and psoriasis. These symptoms are also found in SAPHO syndrome in addition to the articular and cutaneous manifestations.

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SAPHO syndrome can cause masseter muscle involvement

Cited by 3 publications

References 2 publications

Unusual cause of inflammatory backache: SAPHO syndrome

Unusual cause of inflammatory backache: SAPHO syndrome

Extracutaneous/osteoarticular manifestations in patients with SAPHO syndrome

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome may present with extra‐articular and cutaneous manifestations

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