Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination

Wang, Dan-jie; Wang, Xiao; Li, Shu-le; Zhang, Tong-tong; Yang, Ya-chen; Wang, Yu-meng; Zhao, Xiao-qiang; Li, Kun-yu; Wang, Yan-qing; Li, Yan; Zhu, Ke-ying; Wang, Jun

doi:10.1016/j.intimp.2023.111408

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…Some studies have found that the triple therapy of Zhoutian pushing for governor vessel Tiaoji manipulation, bloodstabbing, and acupoint injection has high treatment efficiency, and the vertigo score was considerably improved[ 26 ]. Other studies used tendon acupuncture combined with acupoint injection therapy to treat cervical vertigo, which had a substantial effect on dredging the meridians, adjusting the meridian balance, improving blood supply, and relieving local inflammation[ 27 ]. Previous studies have also shown that the combined treatment of diphenhydramine injection at the Neiguan point can improve the symptoms of vertigo in patients and have a good safety profile[ 28 ].…”

Section: Resultsmentioning

confidence: 99%

Clinical research progress on acupuncture for the treatment of otogenic vertigo

Yi,

Yang,

Wang

et al. 2024

World J Clin Cases

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Otogenic vertigo is a common disorder that affects the vestibular system, which often results in considerable discomfort and impaired daily functioning. Traditional Chinese medicine (TCM), including acupuncture and moxibustion, has been historically utilized to manage the symptoms of vertigo. However, the effectiveness and methodology of these treatments have rarely been investigated in the medical literature. This study reviews the existing literature on the point selection, method, and therapeutic effect of acupuncture and moxibustion to provide a reference for the TCM treatment of otogenic vertigo. A literature search was performed using the PubMed search engine. The terms used included otogenic vertigo, acupuncture treatment, and acupuncture point selection. A total of 34 relevant articles were retrieved from PubMed. These suggest that the clinical treatment of otogenic vertigo should consider the functions of zang-fu organs and meridians and select different acupuncture treatment methods according to syndrome differentiation based on the difference between deficiency and excess. Acupuncture and moxibustion therapy should be based on acupoint selection, considering the syndrome differentiation, supplemented with experience. The treatment of otogenic vertigo with acupuncture and moxibustion refers to the selection of appropriate acupuncture methods under the guidance of TCM theory and following the principles of syndrome, disease, and meridian differentiation. Common acupuncture methods include body acupuncture, auricular acupuncture, scalp acupuncture, acupoint injection, electroacupuncture, and moxibustion. There are many acupuncture and moxibustion acupoints selected for the treatment of otogenic vertigo. Individualized treatment according to the patient’s specific condition is effective and safe, which can help to improve the patient’s vertigo symptoms and cerebral blood perfusion.

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Section: Resultsmentioning

confidence: 99%

Clinical research progress on acupuncture for the treatment of otogenic vertigo

Yi,

Yang,

Wang

et al. 2024

World J Clin Cases

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Acupuncture Effect on Reaction-Time Changes in Parkinson’s Disease Patients—Case Study Series

Pereira,

Greten,

Santos

et al. 2024

JCM

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Background: Parkinson’s Disease (PD) is a progressive neurodegenerative condition associated with deficit in reaction time which can lead to falls, resulting in limited independence, diminished quality of life, heightened rates of institutionalization and increased healthcare costs. We aimed to examine the effects of an acupuncture protocol in motor time response after an auditory stimulus. Methods: This study employed a case series design. Reaction time to exposed rhythmic and random auditory stimuli outcomes were evaluated at six different moments over a month-long acupuncture treatment protocol using the MP 36 system from Biopac Systems. Results: We observed a tendency to have more pronounced improvements in the time response in the more affected side of the body compared with the contralateral one. Patients tended to show better values of response to random auditory stimuli compared to rhythmic auditory ones. We also observed a tendency to obtain better results when considering the accumulative effects of the acupuncture protocol. Conclusions: Our findings indicated a possible role of reaction time as a sensitive and useful tool for motor function assessment in PD patients. Also, from our results, we concluded that the acupuncture protocol used may lead to an improvement in efficacy of motor response after aleatory and rhythmic stimulus; we also found a tendency for a higher efficacy of acupuncture in random stimuli responses in the first stages of the disease. However, further in-depth research, including a statistical evaluation with a larger participant pool, is necessary to validate and confirm these promising results.

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Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination

Cited by 2 publications

References 34 publications

Clinical research progress on acupuncture for the treatment of otogenic vertigo

Clinical research progress on acupuncture for the treatment of otogenic vertigo

Acupuncture Effect on Reaction-Time Changes in Parkinson’s Disease Patients—Case Study Series

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