Sandy: A user-friendly and versatile NGS simulator to facilitate sequencing assay design and optimization
Thiago L. A. Miller,
Helena B. Conceição,
Rafael L. Mercuri
et al.
Abstract:Next-generation sequencing (NGS) is currently the gold standard technique for large-scale genome and transcriptome studies. However, the downstream processing of NGS data is a critical bottleneck that requires difficult decisions regarding data analysis methods and parameters. Simulated or synthetic NGS datasets are practical and cost-effective alternatives for overcoming these difficulties. Simulated NGS datasets have known true values and provide a standardized scenario for driving the development of data an… Show more
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