Sandwich-type channeled chemical hydrogels manufactured by 3D ink-jet printing under freezing conditions using a photochemical process for human cell cultures

Kozicki, Marek; Stempień, Zbigniew; Rokita, Bożena; Dudek, Mariusz

doi:10.1016/j.cej.2023.148401

Cited by 4 publications

(2 citation statements)

References 44 publications

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“…The crosslinking in physical hydrogels primarily occurs through physical interactions such as hydrophobic association, chain aggregation, crystallization, polymer chain complexation, and hydrogen bonding [90]. Chemical hydrogels, on the other hand, are synthesized through covalent crosslinking or post-polymerization [91][92][93]. Dual network hydrogels are formed by combining both physical and chemical crosslinking methods [94][95][96].…”

Section: Advantages Of Hydrogels In the Treatment Of Brain Tumorsmentioning

confidence: 99%

Advances in Hydrogels of Drug Delivery Systems for Local Treatment of Brain Tumors

Yang,

Wang,

et al. 2024

Preprint

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The management of brain tumors presents numerous challenges, despite the employment of multimodal therapies including surgical intervention, radiotherapy, chemotherapy, and immunotherapy. Owing to the distinct location of brain tumors and the presence of the blood-brain barrier (BBB), these tumors exhibit considerable heterogeneity and invasiveness at a histological level. Recent advancements in hydrogel research for the local treatment of brain tumors have sought to overcome the primary challenge of delivering therapeutics past the BBB, thereby ensuring efficient accumulation within brain tumor tissues. This article elaborates on various hydrogel-based delivery vectors, examining their efficacy in the local treatment of brain tumors. Additionally, it reviews the fundamental principles involved in designing intelligent hydrogels that can circumvent the BBB and penetrate larger tumor areas, thereby facilitating precise, controlled drug release. Hydrogel-based drug delivery systems (DDSs) are posited to offer a groundbreaking approach in addressing the challenges and limitations inherent in traditional oncological therapies, which are significantly impeded by the unique structural and pathological characteristics of brain tumors.

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Section: Advantages Of Hydrogels In the Treatment Of Brain Tumorsmentioning

confidence: 99%

Advances in Hydrogels of Drug Delivery Systems for Local Treatment of Brain Tumors

Yang,

Wang,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…(3) Tunability. With varied crosslinking agents and conditions, the crosslinking density and pore structure of chemical hydrogels can be precisely controlled, enabling their properties to be tailored for specific applications [ 123 , 124 , 125 ]. Dual-network hydrogels integrate the strengths of both physical hydrogels and chemical hydrogels via the following characteristics: (1) High strength and toughness.…”

Section: Advantages Of Hydrogels In the Treatment Of Brain Tumorsmentioning

confidence: 99%

Advances in Hydrogels of Drug Delivery Systems for the Local Treatment of Brain Tumors

Yang,

Wang,

et al. 2024

Gels

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The management of brain tumors presents numerous challenges, despite the employment of multimodal therapies including surgical intervention, radiotherapy, chemotherapy, and immunotherapy. Owing to the distinct location of brain tumors and the presence of the blood–brain barrier (BBB), these tumors exhibit considerable heterogeneity and invasiveness at the histological level. Recent advancements in hydrogel research for the local treatment of brain tumors have sought to overcome the primary challenge of delivering therapeutics past the BBB, thereby ensuring efficient accumulation within brain tumor tissues. This article elaborates on various hydrogel-based delivery vectors, examining their efficacy in the local treatment of brain tumors. Additionally, it reviews the fundamental principles involved in designing intelligent hydrogels that can circumvent the BBB and penetrate larger tumor areas, thereby facilitating precise, controlled drug release. Hydrogel-based drug delivery systems (DDSs) are posited to offer a groundbreaking approach to addressing the challenges and limitations inherent in traditional oncological therapies, which are significantly impeded by the unique structural and pathological characteristics of brain tumors.

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Bioinspired 3D printed elastomer-hydrogel hybrid with robust interfacial bonding for flexible ionotronics

Tian,

Yu,

Zuo

et al. 2024

Chemical Engineering Journal

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Sandwich-type channeled chemical hydrogels manufactured by 3D ink-jet printing under freezing conditions using a photochemical process for human cell cultures

Cited by 4 publications

References 44 publications

Advances in Hydrogels of Drug Delivery Systems for Local Treatment of Brain Tumors

Advances in Hydrogels of Drug Delivery Systems for Local Treatment of Brain Tumors

Advances in Hydrogels of Drug Delivery Systems for the Local Treatment of Brain Tumors

Bioinspired 3D printed elastomer-hydrogel hybrid with robust interfacial bonding for flexible ionotronics

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