One-hundred-and-twenty-five articles were selected for the review. The primary function of the cementation is to establish reliable retention, a durable seal of the space between the tooth and the restoration, and to provide adequate optical properties. The various types of cements used in dentistry could be mainly divided into two groups: Water-based cements and polymerizing cements. Water-based cements exhibited satisfying long-term clinical performance associated with cast metal (inlays, onlays, partial crowns) as well as single unit metal-ceramic FDPs and multiple unit FDPs with macroretentive preparation designs and adequate marginal fit. Early short-term clinical results with high-strength all-ceramic restorations luted with water-based cements are also promising. Current polymerizing cements cover almost all fields of water-based cements and in addition to that they are mainly indicated for non-retentive restorations. They are able to seal the tooth completely creating hybrid layer formation. Furthermore, adhesive capabilities of polymerizing cements allowed for bonded restorations, promoting at the same time the preservation of dental tissues.