Same‐day mastectomy and axillary lymph node dissection is safe for most patients with breast cancer

Abstract

Background and Objective The aim of this study was to evaluate the safety of same‐day mastectomy, with or without a sentinel node biopsy (SNB) and/or axillary lymph node dissection (ALND). Methods In this retrospective study, we reviewed 913 consecutive women who underwent a simple mastectomy for breast cancer between the years 2014 and 2019 and were treated either with same‐day surgery (SDS) or an overnight stay (OS) regime. We reviewed all surgical complications, any unplanned return to care (RTC) and the rehospitalization rate for 30 postoperative days. Results A total of 259 patients (28%) were treated with SDS and 654 patients (72%) with an OS regime. There was no difference in RTC (odds ratio: 0.79 [95% confidence interval: 0.53–1.18], p = 0.26) or any major complications between the groups. None of the investigated subgroups, such as patients with previous neoadjuvant therapy, diabetes, obesity (up to a body mass index of 40 kg/m2), the American Society of Anaesthesiologist Class of 3, or elderly patients aged 75–84 years, showed an increased complication rate when treated with the SDS regime. Conclusion A same‐day simple mastectomy is safe with SNB and/or ALND. It can be performed safely for most patients with stable co‐morbidities.

A novel technique of reverse-sequence endoscopic nipple-sparing mastectomy with direct-to-implant breast reconstruction: medium-term oncological safety outcomes and feasibility of 24-h discharge for breast cancer patients

“…Many studies have confirmed that it is safe for breast cancer patients to be discharged within 24 h after mastectomy 21 , 43 – 46 , which were the same as our study. However, it is less feasible to discharge patients who have undergone implant-based breast reconstruction within 24 h at breast centres worldwide, let alone E-NSM with DIBR.…”

Bioinformatics Method Was Used to Analyze the Highly Expressed Gene FAM83A of Breast Cancer in Young Women

“…Initial consultation and molecular targeted therapy necessitate affirmative changes in the key genes of breast cancer progression, conversion, and poor prognosis. The manifestations of VEGF and FAM83A correspond significantly to the various clinical pathological characteristics and prognosis of breast cancer patients and can be regarded as the therapeutic target of breast cancer [ 14 ]. Studies in the literature suggest that some molecular markers are associated with poor prognosis in breast cancer; for example, the human-encoded FAM83A gene is highly expressed in breast cancer.…”

Surgeon Perspectives on Determinants of Same-Day Mastectomy: A Roadmap for Implementing Change

“…Previous studies have demonstrated that patients discharged on the day of MwoR have equivalent surgical outcomes (e.g., complications, reoperations, emergency room visits) with improved patient-reported outcomes (e.g., satisfaction with care) than patients admitted for 1 or more nights, controlling for patient demographics and comorbidities. 9 – 12 There are also data suggesting that differences in surgeon practice patterns, rather than differences in patient demographics or comorbidities, may be driving this practice. 13 Moreover, a review article by the American Society of Breast Surgeons was recently released describing important factors to consider when starting a same-day mastectomy program.…”