Salvage of a Kidney Graft in a Patient With Advanced Carcinoma of the Cervix by Reimplantation of the Graft From the Pelvis to the Upper Abdomen in Preparation for Radiation Therapy

Abouna, G. M.; Micaily, Bizhan; Lee, Dong Hoon; Kumar, Manish; Jahshan, Antoine E.; Lyons, Patricia

doi:10.1097/00007890-199408270-00021

Cited by 9 publications

(14 citation statements)

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“…[3,4] Based on risk factors for the patient's cancer, adjuvant radiation may be recommended but impossible to deliver because of the pelvic kidney. Whole kidney dose constraints are nearly half of the 45-50.4 Gy required to prevent tumor recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…[5] An already grafted kidney may require allograft autotransplantation. [3] Alternatively, the radiation oncologist can block the kidney, but conventional techniques may miss the high-risk target volume. [6] Mouzin et al in 2004 used modern, three-dimensional planning for renal transplant recipients with prostate cancer but their fields were much smaller than the whole pelvis and targeted the prostate only.…”

Section: Discussionmentioning

confidence: 99%

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Adjuvant pelvic irradiation for cervical cancer in the setting of a transplanted pelvic kidney

et al. 2012

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Postoperative radiation therapy is often needed following resection for gynecological cancers. A pelvic kidney, whether ectopic or transplanted, is considered an absolute contraindication for radiation if the organ is left in place. A 45-year-old, immunosuppressed patient with FIGO IB1 cervical adenocarcinoma was treated with intensity-modulated radiation therapy (IMRT) to 45 Gy to the modified whole pelvis with a boost to 59.4 Gy to high-risk areas despite having a transplanted kidney in the right iliac fossa. The irradiation prevented further local failure in the pelvis at 36-month follow-up with no decrement in renal function. Radiation to the modified pelvis using IMRT while avoiding the renal allograft is technically feasible and should be offered to more high-risk patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Adjuvant pelvic irradiation for cervical cancer in the setting of a transplanted pelvic kidney

et al. 2012

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“…We could find 7 case reports concerning this subject [2,4-8]. In 5 cases the primary tumor being treated was a uterine cervix carcinoma [2,6-8].…”

Section: Discussionmentioning

confidence: 99%

Intensity Modulated Radiotherapy (IMRT) in the postoperative treatment of an adenocarcinoma of the endometrium complicated by a pelvic kidney

et al. 2006

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Background: Pelvic Radiotherapy (RT) as a postoperative treatment for endometrial cancer improves local regional control. Brachytherapy also improves vaginal control. Both treatments imply significant side effects that a fine RT technique can help avoiding. Intensity Modulated RT (IMRT) enables the treatment of the target volume while protecting normal tissue. It therefore reduces the incidence and severity of side effects.

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“…There are few data in the literature regarding optimal technique of radiotherapy in patients with pelvic kidney [3][4][5][6][7][8][9][10][11]. There is no definite data about the optimal dose and method of pelvic radiotherapy in patients with pelvic kidney.…”

Section: Radiotherapy In Pelvic Kidneymentioning

confidence: 99%

“…An advanced case of carcinoma cervix, 9 years after renal transplantation has been reported to have undergone successful auto transplantation for delivering extended radical radiotherapy to include even the Para aortic nodes [3]. Transplanting the kidney out of the field of radiation is an attractive option and has been shown to have a good success rate.…”

Section: Rt After Auto Transplantationmentioning

confidence: 99%

Approach to Carcinoma Cervix with Pelvic Kidney

Rajaraman

Muthusamy

Hussain

2010

Indian J Surg Oncol

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To study the management of carcinoma cervix when the patient has an associated pelvic kidney. The simultaneous occurrence of carcinoma cervix and pelvic kidney is rare. It is an interesting scenario where surgery is technically challenging and radiation is difficult since the pelvic kidney lies within the field of radiation. In our department, we treated three cases of cervical carcinoma with pelvic kidney. First case was FIGO IIB treated with external beam radiotherapy followed by radical hysterectomy; second case stage IB1 treated with radical hysterectomy, third case was referred to us after panhysterectomy with carcinoma detected in postoperative histopathological report, and she was treated with external beam radiotherapy. We made an online database search and found few case reports of gynecological malignancies associated with pelvic kidney and reviewed their management. All the three patients are alive and disease free in the last follow up. None of the patients developed uremia. The pelvic kidney of the patients treated with radiotherapy has shrunken in size. Surgery is preferred over radiotherapy in early stages of carcinoma cervix with pelvic kidney to avoid radiation-induced damage to pelvic kidney.

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Salvage of a Kidney Graft in a Patient With Advanced Carcinoma of the Cervix by Reimplantation of the Graft From the Pelvis to the Upper Abdomen in Preparation for Radiation Therapy

Cited by 9 publications

References 0 publications

Adjuvant pelvic irradiation for cervical cancer in the setting of a transplanted pelvic kidney

Adjuvant pelvic irradiation for cervical cancer in the setting of a transplanted pelvic kidney

Intensity Modulated Radiotherapy (IMRT) in the postoperative treatment of an adenocarcinoma of the endometrium complicated by a pelvic kidney

Approach to Carcinoma Cervix with Pelvic Kidney

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