Salvage live donor liver transplantation for a second recurrence of hepatocellular carcinoma

Sotiropoulos, Georgios C.; Treckmann, Jürgen; Molmenti, Ernesto P.; Schmitz, Klaus; Cicinnati, Vito R.; Paul, Andreas; Broelsch, Christoph E.; Malagó, Massimo

doi:10.1111/j.1432-2277.2007.00572.x

Cited by 1 publication

(1 citation statement)

References 23 publications

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“…Since the first report in 1989, living donor liver transplantation (LDLT) has been gradually accepted as a therapeutic modality for end‐stage liver cirrhosis and hepatocellular carcinoma [1–3]. The decision of the choice between the right lobe and extended left lobe depends on the physical constitution of the recipient in LDLT [4,5].…”

Section: Introductionmentioning

confidence: 99%

Congestion of the donor remnant right liver after extended left lobe donation

Fukuhara

Umeda

Toshima

et al. 2009

Transplant International

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Summary The clinical importance of congestion of the remnant right lobe has not yet been fully elucidated in donors who donate their left lobe with the middle hepatic vein. The impact of congestion on clinical course and liver regeneration in 52 donor remnant livers were evaluated. The donors were divided into three groups according to the degree of the congestion: the mild [congestion ratio (CR) < 10%], moderate (CR ranged from 10% to 25%) and severe congestion groups (CR > 25%). The regeneration ratio of the graft at postoperative day 7 (7 POD) was 22.0 ± 14.3% and inversely correlated with the CR in the remnant right lobe (P = 0.003). Aspartate aminotransferase and alanine aminotransferase at 7 POD were significantly higher in the severe CR group in comparison to the mild CR group (P = 0.003 and 0.019, respectively), but those of the three groups were comparable at 30 POD. The hospital stays were significantly longer in the severe CR group (P = 0.010). In conclusion, the congestion of the donors’ remnant right liver can lead the transient liver dysfunction and poor regeneration. Therefore, the conversion of the graft from the left to right lobe might be appropriate according to the degree of the congestion.

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Section: Introductionmentioning

confidence: 99%