Salvage high-dose-rate (HDR) brachytherapy for recurrent head-and-neck cancer

Late nodal metastasis in early-stage node-negative oral cavity cancers after successful sole interstitial brachytherapy: An institutional experience of 42 cases in India

“…excellent long-term data, comparable results are obtained by highedose rate (HDR) brachytherapy (3,10,11), with fewer late complications than were indicated by previously reported data for LDR brachytherapy. Results suggest that interstitial HDR can be recommended in selected patients with first presentation lesions, local or nodal recurrences (12,13), or second primary carcinomas, after surgical resection (14e16), even with a previous course of external beam radiation therapy.…”

High-dose-rate interstitial brachytherapy in recurrent and previously irradiated head and neck cancers—Preliminary results

“…Hepel et al have recently reported their preliminary results in 30 patients with recurrent H&N cancers. Using a 3e4 Gy twice daily fractionation to a median dose of 34 Gy, they reported a 2-year LC and survival of 45% and 37%, respectively (15). The incidence of Grade III/IV complications was 16% in their series.…”

Endoscopy-guided brachytherapy for sinonasal and nasopharyngeal recurrences

“…In addition, vascular adverse events are reported in the literature (10,34), including carotid artery compromise, arterial bleeding at the time of catheter removal, and nonfatal ischemic cerebrovascular accident. Headache, neuroendocrine dysfunction, optic nerve (cranial nerve II)/chiasma injury, and nerve palsy are also reported as chronic radiation complications in some series (35).…”