Salvadoran Celastraceae Species as a Source of Antikinetoplastid Quinonemethide Triterpenoids
Marvin J. Núñez,
Morena L. Martínez,
Ulises G. Castillo
et al.
Abstract:Chagas disease and leishmaniasis are among the most widespread neglected tropical diseases, and their current therapies have limited efficacy and several toxic side effects. The present study reports the chemical and antikinetoplastid profiles of extracts from five Salvadoran Celastraceae species against theTrypanosoma cruzi epimastigotes stage and Leishmania amazonensis and Leishmania donovani promastigote forms. The phytochemical profile evinced the presence of flavonoids, tannins, sterols, and triterpenes a… Show more
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