1950
DOI: 10.1172/jci102344
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Salt Retention in Cirrhosis of the Liver 1

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1951
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Cited by 67 publications
(12 citation statements)
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References 14 publications
(17 reference statements)
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“…Two out of five patients showed an impairment in ERPF and an abnormal elevation of filtration fraction. These findings agree with those reported in the literature (22)(23)(24)(25). It was difficult to cor-relate any impairment of renal function with the severity of the cirrhosis, degree of ascites or with any past history of cardiovascular renal disease.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…Two out of five patients showed an impairment in ERPF and an abnormal elevation of filtration fraction. These findings agree with those reported in the literature (22)(23)(24)(25). It was difficult to cor-relate any impairment of renal function with the severity of the cirrhosis, degree of ascites or with any past history of cardiovascular renal disease.…”
Section: Discussionsupporting
confidence: 89%
“…They observed higher rates of glomerular filtration and effective renal plasma flow in patients without ascites or during active diuresis than in the presence of actively reaccumulating ascites. Patek and associates (23), and more recently Goodyer, Relman, Lawrason, and Epstein (24) observed that mean glomerular filtration rates and effective renal plasma flows were within normal limits in this disease. Farnsworth and Krakusin (25) showed that the electrolyte excretion in patients with hepatic cirrhosis and ascites resembled that seen in cardiac failure.…”
mentioning
confidence: 68%
“…The great veins (42), the right heart and pulmonary artery (43), the cranial cavity (44), the "cephalad portion of the body" (45), and the arterial pressoreceptors (46) (50,51), and hemorrhage (52,53) are associated with a diminution in total blood volume. In quiet standing (6), venous congestion of the limbs (54,55), partial occlusion of the superior or inferior vena cava (56), and portal hypertension (57), filtration from the capillaries is increased and in addition blood is pooled in the peripheral veins, away from the general circulation. Acute (58) and chronic (59,60) constrictive pericarditis, constriction of the pulmonary artery (61,62) and congestive heart failure are characterized by distention of the central veins with blood which the heart is unable to pump efficiently into the aorta.…”
Section: Excretion Of Electrolytes and Watermentioning
confidence: 99%
“…When infusions of hypertonic saline are given to thirsted subjects, the rate of sodium excretion rises, but drops sharply when the serum sodium is suddenly restored to normal by the ingestion of a large quantity of water (49). Some workers have concluded that when an infusion of hypertonic saline is given, "changes in sodium excretion are invoked by differences between extracellular and intracellular osmotic pressures" (50).…”
Section: )mentioning
confidence: 99%