Salmonella Spinal Infection: A Rare Case in a Patient with Advanced AIDS

Berngard, Samuel Clark; Miller, Marshall G.

doi:10.1177/1545109712473778

Cited by 1 publication

(2 citation statements)

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“…Four weeks later, his neck pain worsened, and he was started on prophylactic intravenous antibiotics after a lumbar puncture at an outside facility raised concern for possible bacterial meningitis. The CSF profile demonstrated a white blood cell count of 2160 cells/mm 3 (62% neutrophils), a red blood cell count of 43 cells/mm 3 , a glucose level of 30 mg/dl, a protein level of 252 mg/dl, and a negative Gram stain and culture.…”

Section: History and Physical Examinationmentioning

confidence: 99%

“…While isolated spinal cysticercosis without intracranial involvement is rare, patients with spinal echinococcosis present more often with primary spinal infection. 1,3,5,[7][8][9][10][11][12][13][14][17][18][19][20]22 In a recent review of 467 cases of spinal echinococcosis by Neumayr et al, 13 17.9% were primary spinal infections without intracranial involvement.…”

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confidence: 99%

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Case report of an epidural cervical Onchocerca lupi infection in a 13-year-old boy

Chen

Moon

deMello

et al. 2015

PED

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A 13-year-old boy presented with fever and neck pain and stiffness, which was initially misdiagnosed as culture-negative meningitis. Magnetic resonance images of the brain and cervical spine demonstrated what appeared to be an intradural extramedullary mass at the C1–3 level, resulting in moderate cord compression, and a Chiari Type I malformation. The patient underwent a suboccipital craniectomy and a C1–3 laminectomy with intradural exploration for excisional biopsy and resection. The lesion containing the parasite was extradural, extending laterally through the C2–3 foramina. Inflammatory tissue secondary to Onchocerca lupi infection was identified, and treatment with steroids and doxycycline was initiated. At the 6-month follow-up, the patient remained asymptomatic, with MR images demonstrating a significant reduction in lesional size. However, 10 weeks postoperatively, the infection recurred, necessitating a second operation. The patient was treated with an additional course of doxycycline and is currently maintained on ivermectin therapy. This is the second reported case of cervical O. lupi infection in a human. In the authors' experience, oral doxycycline alone was insufficient in controlling the disease, and the addition of ivermectin therapy was necessary.

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Section: History and Physical Examinationmentioning

confidence: 99%