Salmonella meningitis: report of five cases

Chaudhary, Uma; Sabharwal, U; Tewari, Angela

doi:10.1007/bf02760431

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…In a review of data from the New York Salmonella Center from 1939-1955 by Saphra and Winter [9], only 74 of 9,518 isolates were from the CSF and several extensive reviews of bacterial meningitis reported no cases of Salmonella infection [10,11]. Almost all reported cases have occurred in children, especially infants [1,6,12,13]. In two series of patients with typhoid fever, Osler [14] reported 11 of 2,000 patients with meningitis and Osuntokun [15] noted confusional states in 57% of 959 cases, although meningitis occurred in only 0.2% of cases.…”

Section: Discussionmentioning

confidence: 97%

Salmonella Meningitis: Report of Three Cases in Adults and Literature Review

Karim

Islam

2002

Infection

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Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs almost exclusively in infants and young children. One case of Salmonella meningitis and two cases of cerebrospinal fluid (CSF) pleocytosis in adult patients with Salmonella bacteremia were studied and the literature was reviewed. On a retrospective review of the charts of 100 sequential patients with Salmonella typhi and S. paratyphi-positive blood cultures, we found one patient with fulminant Salmonella meningitis and two others with CSF pleocytosis. All three patients survived. The patient with Salmonella meningitis had significant residual neurologic sequela. Salmonella encephalopathy occurred in six other patients who presented with headache and were confused or drowsy. Cases of meningitis in adults do occur and are associated with a high morbidity and mortality. Newer cephalosporn antibiotics may be the therapy of choice in these infections.

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