Salmonella-like bioadhesive nanoparticles

Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy

“…20,35 Moreover, carboxyl groups generated by the hydrolysis of anhydride groups form hydrogen bonds with other molecules exposed on the cell membrane and with other possible biological targets. 23 This phenomenon can also be explored to increase the incorporation of PS molecules by target cells.…”

Mucosal immunization with Shigella flexneri outer membrane vesicles induced protection in mice

“…These nanoparticles demonstrated their ability to initiate a strong and balanced mucosal immune response and then, to efficiently induce Th-1 subset [5]. In addition, these nanoparticles loaded with different antigens have showed to be effective against experimental challenges with Salmonella or Brucella [6][7][8][9].…”

Immunogenicity of Peanut Proteins Containing Poly(Anhydride) Nanoparticles

“…Likewise, previous studies had described the bioadhesive properties of poly(anhydride) nanoparticles (20). Thus, these polymeric systems present an enhanced interaction with the gut mucosa, a key factor for the induction of strong mucosal immune responses (20)(21)(22). Moreover, it has been demonstrated that the decoration of the surface of poly(anhydride) nanoparticles with specific ligands (i.e., mannosamine or thiamine) increased their recognition and/or their capture by antigen-presenting cells (APCs) (18,19,23), allowing an effective immune response associated with an increased T H 1 profile (24).…”